Human parathyroid hormone gene (PTH) is on short arm of chromosome 11

S. L. Naylor; A. Y. Sakaguchi; P. Szoka; G. N. Hendy; H. M. Kronenberg; A. Rich; T. B. Shows

doi:10.1007/BF01574261

Human parathyroid hormone gene (PTH) is on short arm of chromosome 11

S. L. Naylor
, A. Y. Sakaguchi
, P. Szoka
, G. N. Hendy
, H. M. Kronenberg
, A. Rich
, T. B. Shows

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Abstract

The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTH cDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTH gene was mapped to the short arm of the chromosome 11.

Original language	English (US)
Pages (from-to)	609-616
Number of pages	8
Journal	Somatic Cell Genetics
Volume	9
Issue number	5
DOIs	https://doi.org/10.1007/BF01574261
State	Published - Sep 1983
Externally published	Yes

ASJC Scopus subject areas

Genetics

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10.1007/BF01574261

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title = "Human parathyroid hormone gene (PTH) is on short arm of chromosome 11",

abstract = "The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTH cDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTH gene was mapped to the short arm of the chromosome 11.",

author = "Naylor, \{S. L.\} and Sakaguchi, \{A. Y.\} and P. Szoka and Hendy, \{G. N.\} and Kronenberg, \{H. M.\} and A. Rich and Shows, \{T. B.\}",

year = "1983",

month = sep,

doi = "10.1007/BF01574261",

language = "English (US)",

volume = "9",

pages = "609--616",

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publisher = "Plenum Publishers",

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T1 - Human parathyroid hormone gene (PTH) is on short arm of chromosome 11

AU - Naylor, S. L.

AU - Sakaguchi, A. Y.

AU - Szoka, P.

AU - Hendy, G. N.

AU - Kronenberg, H. M.

AU - Rich, A.

AU - Shows, T. B.

PY - 1983/9

Y1 - 1983/9

N2 - The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTH cDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTH gene was mapped to the short arm of the chromosome 11.

AB - The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTH cDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTH gene was mapped to the short arm of the chromosome 11.

UR - https://www.scopus.com/pages/publications/0021041497

UR - https://www.scopus.com/pages/publications/0021041497#tab=citedBy

U2 - 10.1007/BF01574261

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EP - 616

JO - Somatic Cell Genetics

JF - Somatic Cell Genetics

IS - 5

ER -

Human parathyroid hormone gene (PTH) is on short arm of chromosome 11

Abstract

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