Human immunoglobulin therapy for preeclampsia associated with lupus anticoagulant and anticardiolipin antibody

Vern L. Katz, John M. Thorp, William J. Watson, Larry Fowler, R. Phillip Heine

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

A patient with lupus anticoagulant and anticardiolipin anti-body developed preeclampsia at 24 weeks’ gestation. Therapy with human immunoglobulin (Ig) resulted in stabilization of preeclampsia and suppression of the lupus anticoagulant. Anticardiolipin antibody titers were partially suppressed. Preeclampsia worsened at 32 weeks’ gestation, and a healthy infant was delivered. For patients with preeclampsia secondary to lupus anticoagulant before the fetus is viable, human Ig is a potential therapeutic option.

Original languageEnglish (US)
Pages (from-to)986-988
Number of pages3
JournalObstetrics and gynecology
Volume76
Issue number5
DOIs
StatePublished - Nov 1990
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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