Abstract
A young woman with systemic lupus erythematosus (SLE) was infected with human immunodeficiency virus 1 (HIV-1) and about 6 years later developed persistent bilateral parotid gland enlargement. It was unclear whether this represented salivary gland involvement as a component of her SLE (secondary Sjogren's syndrome) or the initial clinical manifestation of her HIV-1 infection. HIV proviral DNA was found in individual salivary glandular secretions and in whole saliva. Additionally, cells positive for HIV RNA were isolated from whole saliva. A parotid gland biopsy revealed infiltrating lymphocytes containing large amounts of HIV RNA.
Original language | English (US) |
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Pages (from-to) | 1810-1812 |
Number of pages | 3 |
Journal | Journal of Rheumatology |
Volume | 19 |
Issue number | 11 |
State | Published - Jan 1 1992 |
Externally published | Yes |
Keywords
- HIV
- SLE
- oral
- parotid
- saliva
- salivary gland
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Immunology