Abstract
A young woman with systemic lupus erythematosus (SLE) was infected with human immunodeficiency virus 1 (HIV-1) and about 6 years later developed persistent bilateral parotid gland enlargement. It was unclear whether this represented salivary gland involvement as a component of her SLE (secondary Sjogren's syndrome) or the initial clinical manifestation of her HIV-1 infection. HIV proviral DNA was found in individual salivary glandular secretions and in whole saliva. Additionally, cells positive for HIV RNA were isolated from whole saliva. A parotid gland biopsy revealed infiltrating lymphocytes containing large amounts of HIV RNA.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1810-1812 |
| Number of pages | 3 |
| Journal | Journal of Rheumatology |
| Volume | 19 |
| Issue number | 11 |
| State | Published - 1992 |
| Externally published | Yes |
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Keywords
- HIV
- oral
- parotid
- saliva
- salivary gland
- SLE
ASJC Scopus subject areas
- Immunology
- Rheumatology
Cite this
Human immunodeficiency virus (HIV) and HIV infected cells in saliva and salivary glands of a patient with systemic lupus erythematosus. / Yeh, Chih-ko; Fox, P. C.; Goto, Y.; Austin, J. A.; Brahim, J. S.; Fox, C. H.
In: Journal of Rheumatology, Vol. 19, No. 11, 1992, p. 1810-1812.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Human immunodeficiency virus (HIV) and HIV infected cells in saliva and salivary glands of a patient with systemic lupus erythematosus
AU - Yeh, Chih-ko
AU - Fox, P. C.
AU - Goto, Y.
AU - Austin, J. A.
AU - Brahim, J. S.
AU - Fox, C. H.
PY - 1992
Y1 - 1992
N2 - A young woman with systemic lupus erythematosus (SLE) was infected with human immunodeficiency virus 1 (HIV-1) and about 6 years later developed persistent bilateral parotid gland enlargement. It was unclear whether this represented salivary gland involvement as a component of her SLE (secondary Sjogren's syndrome) or the initial clinical manifestation of her HIV-1 infection. HIV proviral DNA was found in individual salivary glandular secretions and in whole saliva. Additionally, cells positive for HIV RNA were isolated from whole saliva. A parotid gland biopsy revealed infiltrating lymphocytes containing large amounts of HIV RNA.
AB - A young woman with systemic lupus erythematosus (SLE) was infected with human immunodeficiency virus 1 (HIV-1) and about 6 years later developed persistent bilateral parotid gland enlargement. It was unclear whether this represented salivary gland involvement as a component of her SLE (secondary Sjogren's syndrome) or the initial clinical manifestation of her HIV-1 infection. HIV proviral DNA was found in individual salivary glandular secretions and in whole saliva. Additionally, cells positive for HIV RNA were isolated from whole saliva. A parotid gland biopsy revealed infiltrating lymphocytes containing large amounts of HIV RNA.
KW - HIV
KW - oral
KW - parotid
KW - saliva
KW - salivary gland
KW - SLE
UR - http://www.scopus.com/inward/record.url?scp=0026465588&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026465588&partnerID=8YFLogxK
M3 - Article
C2 - 1491408
AN - SCOPUS:0026465588
VL - 19
SP - 1810
EP - 1812
JO - Journal of Rheumatology
JF - Journal of Rheumatology
SN - 0315-162X
IS - 11
ER -