Human cognitive and neuro-psychiatric bio-markers in the cardiac peri-operative patient

H. J. Reis, A. C.P. de Oliveira, M. A. Mukhamedyarov, A. L. Zefirov, A. A. Rizvanov, M. E. Yalvaç, A. L. Teixeira, Z. Janka, A. Hussain, L. B. Vieira, A. Palotás

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Some of the complexities of surgical interventions include neurological and psychiatric disturbances. Prompt identification and early treatment of these complications are pivotal in achieving excellent clinical results. Recognizing major adverse events such as stroke, seizure or delirium is usually straight-forward, however the discovery of less frequent or more subtle post-operative changes such as cognitive dysfunction might be delayed due to lack of appropriate diagnostic tools. This review summarizes biological markers that can be utilized as surrogates in evaluating surgery-related neuro-psychiatric disorders.

Original languageEnglish (US)
Pages (from-to)1155-1163
Number of pages9
JournalCurrent Molecular Medicine
Issue number9
StatePublished - Jan 1 2014
Externally publishedYes


  • Bio-marker
  • Complication
  • Peri-operative period
  • Post-operative cognitive decline
  • Surgery

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology


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