Human Chorionic Gonadotropin in Human Neoplastic Cells

Linda M Mcmanus, Michael A. Naughton, Antonio Martinez-Hernandez

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Peroxidase-labeled antibody against the β chain of human chorionic gonadotropin was used to demonstrate that 25 human malignant tumors contained this antigen. The antigen was localized both in the cytoplasm and on the surface of the malignant cells. Human chorionic gonadotropin may be responsible for both selective maternal immunosuppression by fetal tissue and host immunosuppression by tumors.

Original languageEnglish (US)
Pages (from-to)3476-3481
Number of pages6
JournalCancer Research
Volume36
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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  • Cite this

    Mcmanus, L. M., Naughton, M. A., & Martinez-Hernandez, A. (1976). Human Chorionic Gonadotropin in Human Neoplastic Cells. Cancer Research, 36, 3476-3481.