How Ebola and Marburg viruses battle the immune system

Mansour Mohamadzadeh, Lieping Chen, Alan L. Schmaljohn

Research output: Contribution to journalReview articlepeer-review

100 Scopus citations

Abstract

The filoviruses Ebola and Marburg have emerged in the past decade from relative obscurity to serve now as archetypes for some of the more intriguing and daunting challenges posed by such agents. Public imagination is captured by deadly outbreaks of these viruses and reinforced by the specter of bioterrorism. As research on these agents has accelerated, it has been found increasingly that filoviruses use a combination of familiar and apparently new ways to baffle and battle the immune system. Filoviruses have provided thereby a new lens through which to examine the immune system itself.

Original languageEnglish (US)
Pages (from-to)556-567
Number of pages12
JournalNature Reviews Immunology
Volume7
Issue number7
DOIs
StatePublished - Jul 2007
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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