Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents

G. SCOTT WATERMAN; NEAL D. RYAN; JOAQUIM PUIG-ANTICH; VIVECA MEYER; PAUL J. AMBROSINI; HARRIS RABINOVICH; STACY STULL; HANA NOVACENKO; DOUGLAS E. WILLIAMSON; BEVERLY NELSON

doi:10.1097/00004583-199105000-00010

Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents

G. SCOTT WATERMAN, NEAL D. RYAN, JOAQUIM PUIG-ANTICH, VIVECA MEYER, PAUL J. AMBROSINI, HARRIS RABINOVICH, STACY STULL, HANA NOVACENKO, DOUGLAS E. WILLIAMSON, BEVERLY NELSON

Epidemiology & Biostatistics

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Because of its neuroendocrine effects, amphetamine infusion has been used as a probe to investigate neurobiological correlates of depressive illness. In two separate studies, a total of 72 adolescents with major depressive disorder and 66 normal adolescents were given dextroamphetamine, 0.15 mg/kg, intravenously. Their cortisol, growth hormone, and prolactin responses were measured. These endocrine responses did not reliably distinguish adolescents with major depressive disorder from those without it, nor did they reliably delineate any specific depressive subgroup. These findings are compared with those from similar studies of adult depression.

Original language	English (US)
Pages (from-to)	415-422
Number of pages	8
Journal	Journal of the American Academy of Child and Adolescent Psychiatry
Volume	30
Issue number	3
DOIs	https://doi.org/10.1097/00004583-199105000-00010
State	Published - Jan 1 1991

Keywords

adolescence
amphetamine
depression
neuroendocrine

ASJC Scopus subject areas

Developmental and Educational Psychology
Psychiatry and Mental health

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WATERMAN, G. SCOTT., RYAN, NEAL. D., PUIG-ANTICH, JOAQUIM., MEYER, VIVECA., AMBROSINI, PAUL. J., RABINOVICH, HARRIS., STULL, STACY., NOVACENKO, HANA., WILLIAMSON, DOUGLAS. E., & NELSON, BEVERLY. (1991). Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 30(3), 415-422. https://doi.org/10.1097/00004583-199105000-00010

Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents. / WATERMAN, G. SCOTT; RYAN, NEAL D.; PUIG-ANTICH, JOAQUIM; MEYER, VIVECA; AMBROSINI, PAUL J.; RABINOVICH, HARRIS; STULL, STACY; NOVACENKO, HANA; WILLIAMSON, DOUGLAS E.; NELSON, BEVERLY.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 30, No. 3, 01.01.1991, p. 415-422.

Research output: Contribution to journal › Article › peer-review

WATERMAN, GSCOTT, RYAN, NEALD, PUIG-ANTICH, JOAQUIM, MEYER, VIVECA, AMBROSINI, PAULJ, RABINOVICH, HARRIS, STULL, STACY, NOVACENKO, HANA, WILLIAMSON, DOUGLASE & NELSON, BEVERLY 1991, 'Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 30, no. 3, pp. 415-422. https://doi.org/10.1097/00004583-199105000-00010

WATERMAN, G. SCOTT ; RYAN, NEAL D. ; PUIG-ANTICH, JOAQUIM ; MEYER, VIVECA ; AMBROSINI, PAUL J. ; RABINOVICH, HARRIS ; STULL, STACY ; NOVACENKO, HANA ; WILLIAMSON, DOUGLAS E. ; NELSON, BEVERLY. / Hormonal Responses to Dextroamphetamine in Depressed and Normal Adolescents. In: Journal of the American Academy of Child and Adolescent Psychiatry. 1991 ; Vol. 30, No. 3. pp. 415-422.

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