Abstract
A λgt11 library of Mycoplasma genitalium genomic DNA was generated, and clones were identified using a pool of monoclonal antibodies directed against different epitopes of the 140 kDa adhesin protein. Because the 140 kDa protein of M. genitalium and the 170 kDa P1 adhesin of M. pneumoniae share biological properties such as a tip-associated location, cytadherence function and immunologic crossreactivity, we performed Southern blot analysis using these cloned partial 140 kDa gene fragments and 14 subclones that span the P1 structural gene of M. pneumoniae. Homologous regions of the two genes were identified.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 69-73 |
| Number of pages | 5 |
| Journal | Microbial Pathogenesis |
| Volume | 6 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1989 |
Keywords
- DNA homology
- Mycoplasma
- adhesins
ASJC Scopus subject areas
- Microbiology
- Infectious Diseases
Fingerprint Dive into the research topics of 'Homologous regions shared by adhesin genes of Mycoplasma pneumoniae and Mycoplasma genitalium'. Together they form a unique fingerprint.
Cite this
Dallo, S. F., Norton, J. R., Su, C. J., & Baseman, J. B. (1989). Homologous regions shared by adhesin genes of Mycoplasma pneumoniae and Mycoplasma genitalium. Microbial Pathogenesis, 6(1), 69-73. https://doi.org/10.1016/0882-4010(89)90009-0