HLA and DR antigen frequencies in melanoma patients: possible relation to disease prognosis

Marilyn S. Pollack; Philip O. Livingston

doi:10.1111/j.1399-0039.1985.tb00970.x

HLA and DR antigen frequencies in melanoma patients: possible relation to disease prognosis

Marilyn S. Pollack, Philip O. Livingston

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The frequency of HLA‐DR5 was significantly increased in a large group of malignant melanoma patients (33.7% vs 20.5% for controls). The subgroup of patients with poor prognosis showed both a DR5 increase and a relative decrease in DR1. Although none of these differences was significant after correction for the number of antigens tested, similar findings have been made for other malignancies and further studies should be encouraged.

Original language	English (US)
Pages (from-to)	262-265
Number of pages	4
Journal	Tissue Antigens
Volume	26
Issue number	4
DOIs	https://doi.org/10.1111/j.1399-0039.1985.tb00970.x
State	Published - Oct 1985
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Biochemistry
Genetics

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10.1111/j.1399-0039.1985.tb00970.x

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title = "HLA and DR antigen frequencies in melanoma patients: possible relation to disease prognosis",

abstract = "The frequency of HLA‐DR5 was significantly increased in a large group of malignant melanoma patients (33.7% vs 20.5% for controls). The subgroup of patients with poor prognosis showed both a DR5 increase and a relative decrease in DR1. Although none of these differences was significant after correction for the number of antigens tested, similar findings have been made for other malignancies and further studies should be encouraged.",

author = "Pollack, {Marilyn S.} and Livingston, {Philip O.}",

year = "1985",

month = oct,

doi = "10.1111/j.1399-0039.1985.tb00970.x",

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T2 - possible relation to disease prognosis

AU - Pollack, Marilyn S.

AU - Livingston, Philip O.

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N2 - The frequency of HLA‐DR5 was significantly increased in a large group of malignant melanoma patients (33.7% vs 20.5% for controls). The subgroup of patients with poor prognosis showed both a DR5 increase and a relative decrease in DR1. Although none of these differences was significant after correction for the number of antigens tested, similar findings have been made for other malignancies and further studies should be encouraged.

AB - The frequency of HLA‐DR5 was significantly increased in a large group of malignant melanoma patients (33.7% vs 20.5% for controls). The subgroup of patients with poor prognosis showed both a DR5 increase and a relative decrease in DR1. Although none of these differences was significant after correction for the number of antigens tested, similar findings have been made for other malignancies and further studies should be encouraged.

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HLA and DR antigen frequencies in melanoma patients: possible relation to disease prognosis

Abstract

ASJC Scopus subject areas

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