Hiv infection of human gastrointestinal submucosal cells: An in vitro model that mimics kaposi's sarcoma

Mary Pat Moyer; Adolph Ramirez; Anthony Woolf; Rachel I. Huot; Miguel S. McKee-Suarez

doi:10.1007/BF02630911

Hiv infection of human gastrointestinal submucosal cells: An in vitro model that mimics kaposi's sarcoma

Mary Pat Moyer, Adolph Ramirez, Anthony Woolf, Rachel I. Huot, Miguel S. McKee-Suarez

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Infection of human gastrointestinal submucosal mesenchymal cells with HIV-1 led to cell populations with abnormal growth properties, increased synthesis of endothelial cell and angioblast markers, and release of angiogenic factors. This system may be the first in vitro model for HIV-induced Kaposi's sarcoma.

Original language	English (US)
Pages (from-to)	337-344
Number of pages	8
Journal	In Vitro Cellular & Developmental Biology
Volume	27
Issue number	4
DOIs	https://doi.org/10.1007/BF02630911
State	Published - Apr 1991

Keywords

HIV-1
Kaposi's sarcoma
gastrointestinal tract
human cell culture
in vitro transformation

ASJC Scopus subject areas

Developmental Biology
Clinical Biochemistry
Cell Biology

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10.1007/BF02630911

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title = "Hiv infection of human gastrointestinal submucosal cells: An in vitro model that mimics kaposi's sarcoma",

abstract = "Infection of human gastrointestinal submucosal mesenchymal cells with HIV-1 led to cell populations with abnormal growth properties, increased synthesis of endothelial cell and angioblast markers, and release of angiogenic factors. This system may be the first in vitro model for HIV-induced Kaposi's sarcoma.",

keywords = "HIV-1, Kaposi's sarcoma, gastrointestinal tract, human cell culture, in vitro transformation",

author = "Moyer, \{Mary Pat\} and Adolph Ramirez and Anthony Woolf and Huot, \{Rachel I.\} and McKee-Suarez, \{Miguel S.\}",

year = "1991",

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AU - Woolf, Anthony

AU - Huot, Rachel I.

AU - McKee-Suarez, Miguel S.

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N2 - Infection of human gastrointestinal submucosal mesenchymal cells with HIV-1 led to cell populations with abnormal growth properties, increased synthesis of endothelial cell and angioblast markers, and release of angiogenic factors. This system may be the first in vitro model for HIV-induced Kaposi's sarcoma.

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KW - Kaposi's sarcoma

KW - gastrointestinal tract

KW - human cell culture

KW - in vitro transformation

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Hiv infection of human gastrointestinal submucosal cells: An in vitro model that mimics kaposi's sarcoma

Abstract

Keywords

ASJC Scopus subject areas

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