High prevalence of angina pectoris in Mexican-American men. A population with reduced risk of myocardial infraction

Braxton D. Mitchell, Helen P Hazuda, Steven M. Haffner, Judith K. Patterson, Michael P. Stern

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Mexican-American men experience lower rates of cardiovascular mortality and have a lower prevalence of nonfatal myocardial infarction than do non-Hispanic white men. To see if this ethnic difference exists for other cardiovascular end points, we compared the prevalence of angina pectoris, as assessed by the Rose Angina Questionnaire, between Mexican Americans (n = 3272) and non-Hispanic whites (n = 1848) examined in the San Antonio Heart Study, a population-based survey of cardiovascular disease and diabetes conducted in San Antonio, Texas, between 1979 and 1988. Contrary to our expectations, angina prevalence was approximately twice as high in Mexican Americans as in non-Hispanic whites, with age-adjusted odds ratios of 2.01 (95% confidence interval (CI), 1.13 to 3.58; P = .02) in men and 1.84 (95% CI, 1.26 to 2.70; P = .001) in women. After controlling for age, body mass index, diabetes status, cigarette smoking, and educational level by logistic regression analysis, angina prevalence remained statistically associated with Mexican American ethnicity in men, but not women. There was little ethnic difference in the proportion of Mexican-American and non-Hispanic white subjects who reported nonspecific chest pain (chest pain not meeting the Rose criteria), suggesting that the ethnic difference in angina prevalence was not an artifact of reporting bias. This was further supported by the fact that the conventional cardiovascular risk factors were more strongly associated with angina prevalence in Mexican Americans than in non-Hispanic whites. These data suggest that Mexican-American men experience high rates of angina despite low rates of myocardial infarction. Future studies should investigate ethnic factors that may have differential effects on the various manifestations of coronary heart disease.

Original languageEnglish (US)
Pages (from-to)415-426
Number of pages12
JournalAnnals of Epidemiology
Volume1
Issue number5
DOIs
StatePublished - 1991

Fingerprint

Angina Pectoris
Population
Chest Pain
Myocardial Infarction
Confidence Intervals
Artifacts
Coronary Disease
Body Mass Index
Cardiovascular Diseases
Logistic Models
Smoking
Odds Ratio
Regression Analysis
Mortality

Keywords

  • Angina pectoris
  • cholesterol
  • coronary disease
  • Mexican Americans

ASJC Scopus subject areas

  • Medicine(all)
  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

High prevalence of angina pectoris in Mexican-American men. A population with reduced risk of myocardial infraction. / Mitchell, Braxton D.; Hazuda, Helen P; Haffner, Steven M.; Patterson, Judith K.; Stern, Michael P.

In: Annals of Epidemiology, Vol. 1, No. 5, 1991, p. 415-426.

Research output: Contribution to journalArticle

Mitchell, Braxton D. ; Hazuda, Helen P ; Haffner, Steven M. ; Patterson, Judith K. ; Stern, Michael P. / High prevalence of angina pectoris in Mexican-American men. A population with reduced risk of myocardial infraction. In: Annals of Epidemiology. 1991 ; Vol. 1, No. 5. pp. 415-426.
@article{5ba743c919ed473ea5a6fcbf5bbfefee,
title = "High prevalence of angina pectoris in Mexican-American men. A population with reduced risk of myocardial infraction",
abstract = "Mexican-American men experience lower rates of cardiovascular mortality and have a lower prevalence of nonfatal myocardial infarction than do non-Hispanic white men. To see if this ethnic difference exists for other cardiovascular end points, we compared the prevalence of angina pectoris, as assessed by the Rose Angina Questionnaire, between Mexican Americans (n = 3272) and non-Hispanic whites (n = 1848) examined in the San Antonio Heart Study, a population-based survey of cardiovascular disease and diabetes conducted in San Antonio, Texas, between 1979 and 1988. Contrary to our expectations, angina prevalence was approximately twice as high in Mexican Americans as in non-Hispanic whites, with age-adjusted odds ratios of 2.01 (95{\%} confidence interval (CI), 1.13 to 3.58; P = .02) in men and 1.84 (95{\%} CI, 1.26 to 2.70; P = .001) in women. After controlling for age, body mass index, diabetes status, cigarette smoking, and educational level by logistic regression analysis, angina prevalence remained statistically associated with Mexican American ethnicity in men, but not women. There was little ethnic difference in the proportion of Mexican-American and non-Hispanic white subjects who reported nonspecific chest pain (chest pain not meeting the Rose criteria), suggesting that the ethnic difference in angina prevalence was not an artifact of reporting bias. This was further supported by the fact that the conventional cardiovascular risk factors were more strongly associated with angina prevalence in Mexican Americans than in non-Hispanic whites. These data suggest that Mexican-American men experience high rates of angina despite low rates of myocardial infarction. Future studies should investigate ethnic factors that may have differential effects on the various manifestations of coronary heart disease.",
keywords = "Angina pectoris, cholesterol, coronary disease, Mexican Americans",
author = "Mitchell, {Braxton D.} and Hazuda, {Helen P} and Haffner, {Steven M.} and Patterson, {Judith K.} and Stern, {Michael P.}",
year = "1991",
doi = "10.1016/1047-2797(91)90011-Z",
language = "English (US)",
volume = "1",
pages = "415--426",
journal = "Annals of Epidemiology",
issn = "1047-2797",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - High prevalence of angina pectoris in Mexican-American men. A population with reduced risk of myocardial infraction

AU - Mitchell, Braxton D.

AU - Hazuda, Helen P

AU - Haffner, Steven M.

AU - Patterson, Judith K.

AU - Stern, Michael P.

PY - 1991

Y1 - 1991

N2 - Mexican-American men experience lower rates of cardiovascular mortality and have a lower prevalence of nonfatal myocardial infarction than do non-Hispanic white men. To see if this ethnic difference exists for other cardiovascular end points, we compared the prevalence of angina pectoris, as assessed by the Rose Angina Questionnaire, between Mexican Americans (n = 3272) and non-Hispanic whites (n = 1848) examined in the San Antonio Heart Study, a population-based survey of cardiovascular disease and diabetes conducted in San Antonio, Texas, between 1979 and 1988. Contrary to our expectations, angina prevalence was approximately twice as high in Mexican Americans as in non-Hispanic whites, with age-adjusted odds ratios of 2.01 (95% confidence interval (CI), 1.13 to 3.58; P = .02) in men and 1.84 (95% CI, 1.26 to 2.70; P = .001) in women. After controlling for age, body mass index, diabetes status, cigarette smoking, and educational level by logistic regression analysis, angina prevalence remained statistically associated with Mexican American ethnicity in men, but not women. There was little ethnic difference in the proportion of Mexican-American and non-Hispanic white subjects who reported nonspecific chest pain (chest pain not meeting the Rose criteria), suggesting that the ethnic difference in angina prevalence was not an artifact of reporting bias. This was further supported by the fact that the conventional cardiovascular risk factors were more strongly associated with angina prevalence in Mexican Americans than in non-Hispanic whites. These data suggest that Mexican-American men experience high rates of angina despite low rates of myocardial infarction. Future studies should investigate ethnic factors that may have differential effects on the various manifestations of coronary heart disease.

AB - Mexican-American men experience lower rates of cardiovascular mortality and have a lower prevalence of nonfatal myocardial infarction than do non-Hispanic white men. To see if this ethnic difference exists for other cardiovascular end points, we compared the prevalence of angina pectoris, as assessed by the Rose Angina Questionnaire, between Mexican Americans (n = 3272) and non-Hispanic whites (n = 1848) examined in the San Antonio Heart Study, a population-based survey of cardiovascular disease and diabetes conducted in San Antonio, Texas, between 1979 and 1988. Contrary to our expectations, angina prevalence was approximately twice as high in Mexican Americans as in non-Hispanic whites, with age-adjusted odds ratios of 2.01 (95% confidence interval (CI), 1.13 to 3.58; P = .02) in men and 1.84 (95% CI, 1.26 to 2.70; P = .001) in women. After controlling for age, body mass index, diabetes status, cigarette smoking, and educational level by logistic regression analysis, angina prevalence remained statistically associated with Mexican American ethnicity in men, but not women. There was little ethnic difference in the proportion of Mexican-American and non-Hispanic white subjects who reported nonspecific chest pain (chest pain not meeting the Rose criteria), suggesting that the ethnic difference in angina prevalence was not an artifact of reporting bias. This was further supported by the fact that the conventional cardiovascular risk factors were more strongly associated with angina prevalence in Mexican Americans than in non-Hispanic whites. These data suggest that Mexican-American men experience high rates of angina despite low rates of myocardial infarction. Future studies should investigate ethnic factors that may have differential effects on the various manifestations of coronary heart disease.

KW - Angina pectoris

KW - cholesterol

KW - coronary disease

KW - Mexican Americans

UR - http://www.scopus.com/inward/record.url?scp=0025883015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025883015&partnerID=8YFLogxK

U2 - 10.1016/1047-2797(91)90011-Z

DO - 10.1016/1047-2797(91)90011-Z

M3 - Article

C2 - 1669522

AN - SCOPUS:0025883015

VL - 1

SP - 415

EP - 426

JO - Annals of Epidemiology

JF - Annals of Epidemiology

SN - 1047-2797

IS - 5

ER -