High blood alcohol levels in women

Helmut K. Seitz, Gerlinde Egerer, Ulrich A. Simanowski, Michael Phillips, George D. Sweeney, Morris S. Zedeck, James L. York, Joel J. Alpert, Barry Zuckerman, Mario Frezza, Carlo di Padova, Enrique Baraona, Charles S. Lieber, Steven Schenker, K. Vincent Speeg

Research output: Contribution to journalLetterpeer-review

16 Scopus citations


To the Editor: The article by Frezza et al. (Jan. 11 issue)1 demonstrates higher blood ethanol concentrations in women than in men because of a decreased activity of gastric alcohol dehydrogenase (ADH). However, there is one important point we would like to focus on. Only younger women (<50 years of age) seem to have significantly lower gastric ADH activities in biopsy specimens from the antrum and corpus of the stomach than men; with advanced age this difference is no longer detectable (Table 1). Older women probably have even higher gastric ADH activities than men of similar age, because gastric.

Original languageEnglish (US)
Pages (from-to)58-62
Number of pages5
JournalNew England Journal of Medicine
Issue number1
StatePublished - Jul 5 1990

ASJC Scopus subject areas

  • Medicine(all)


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