Hereditary cancer syndromes with high risk of endometrial and ovarian cancer: Surgical options for personalized care

Georgia A. McCann, Eric L. Eisenhauer

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Cancer genomics has increased our recognition of specific hereditary cancer mutations. Hereditary breast and ovarian cancer (HBOC) syndrome and Lynch syndrome are two such entities in which women carrying specific mutations may be at high risk for developing breast, ovarian, and/or endometrial cancers. Risk reducing surgery such as prophylactic mastectomy, oophorectomy, and/or hysterectomy may allow women to decrease these risks after completing childbearing. Background, indications, and consequences of these procedures are reviewed.

Original languageEnglish (US)
Pages (from-to)118-124
Number of pages7
JournalJournal of Surgical Oncology
Volume111
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • BRCA
  • Hereditary cancer
  • Lynch

ASJC Scopus subject areas

  • Surgery
  • Oncology

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