Hepadnavirus infection in captive gibbons

Robert E. Lanford, Deborah Chavez, Rebeca Rico-Hesse, Alan Mootnick

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


The recent isolation of a nonhuman primate hepadnavirus from woolly monkeys prompted an examination of other primates for potentially new hepadnaviruses. A serological analysis of 30 captive gibbons revealed that 47% were positive for at least one marker of ongoing or previous infection with a hepatitis B virus (HBV). The amino acid sequences of the core and surface genes of human and gibbon virus isolates were very similar. Phylogenetic analysis indicated that the gibbon isolates lie within the human HBV family, indicating that these HBV isolates most likely stem from infection of gibbons from a human source.

Original languageEnglish (US)
Pages (from-to)2955-2959
Number of pages5
JournalJournal of virology
Issue number6
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology


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