Hepadnavirus infection in captive gibbons

Robert E. Lanford, Deborah Chavez, Rebeca Rico-Hesse, Alan Mootnick

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations


    The recent isolation of a nonhuman primate hepadnavirus from woolly monkeys prompted an examination of other primates for potentially new hepadnaviruses. A serological analysis of 30 captive gibbons revealed that 47% were positive for at least one marker of ongoing or previous infection with a hepatitis B virus (HBV). The amino acid sequences of the core and surface genes of human and gibbon virus isolates were very similar. Phylogenetic analysis indicated that the gibbon isolates lie within the human HBV family, indicating that these HBV isolates most likely stem from infection of gibbons from a human source.

    Original languageEnglish (US)
    Pages (from-to)2955-2959
    Number of pages5
    JournalJournal of virology
    Issue number6
    StatePublished - 2000

    ASJC Scopus subject areas

    • Microbiology
    • Immunology
    • Insect Science
    • Virology

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