Healing at molar extraction sites using freeze-dried bone allograft and collagen wound dressing: Case series and three-arm analyses

Shaimaa M. Al Harthi, Thomas J. Prihoda, Brian L. Mealey, David J. Lasho, Marcel Noujeim, Guy Huynh-Ba

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: Ridge preservation limits dimensional changes after tooth extraction. However, it is still unclear if using a membrane may be advantageous over a collagen wound dressing. Therefore, the goal of this report was to evaluate the outcomes of ridge preservation using freeze-dried bone allograft with a collagen wound dressing. Materials and Methods: This study included 21 patients who had one molar extracted, and the site received ridge preservation using freeze-dried bone allograft and a collagen wound dressing (test 2 group). Patients had two standardized cone beam computed tomography (CBCT) scans, taken within 72 hours and 3 months after extraction, to measure changes in ridge height and width, and buccal and lingual plate thicknesses. Changes in keratinized tissue width were recorded. Three-arm analyses were performed using historic data from a previous randomized controlled trial by the same study group, in which 20 molar sites received a collagen wound dressing alone (control) and 20 received ridge preservation with freezedried bone allograft and a dense polytetrafluoroethylene membrane (test 1) using the same methodology. Results: There was a statistically significant difference in mean buccal ridge height changes between the control group (2.6 ± 2.06 mm) and test 2 group (1.55 ± 0.93 mm) but no difference in ridge and keratinized tissue width changes between groups. No correlation was found between buccal plate thickness and ridge width change. Conclusion: Freeze-dried bone allograft with collagen wound dressing as a barrier was used successfully for ridge preservation in intact molar extraction sites (< 50% bone loss) and can be considered as a treatment alternative to freeze-dried bone allograft with a dense polytetrafluoroethylene membrane.

Original languageEnglish (US)
Pages (from-to)1202-1212
Number of pages11
JournalInternational Journal of Oral and Maxillofacial Implants
Issue number5
StatePublished - 2019


  • Allografts
  • Bone
  • Cone beam computed tomography
  • Dental implants
  • Molar
  • Tooth extraction

ASJC Scopus subject areas

  • Oral Surgery


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