Healing at Molar Extraction Sites Using Freeze-Dried Bone Allograft and Collagen Wound Dressing: Case Series and Three-Arm Analyses

Shaimaa M. Al Harthi, Thomas J. Prihoda, Brian L. Mealey, David J Lasho, Marcel E Noujeim, Guy Huynh-ba

Research output: Contribution to journalArticle

Abstract

PURPOSE: Ridge preservation limits dimensional changes after tooth extraction. However, it is still unclear if using a membrane may be advantageous over a collagen wound dressing. Therefore, the goal of this report was to evaluate the outcomes of ridge preservation using freeze-dried bone allograft with a collagen wound dressing. MATERIALS AND METHODS: This study included 21 patients who had one molar extracted, and the site received ridge preservation using freeze-dried bone allograft and a collagen wound dressing (test 2 group). Patients had two standardized cone beam computed tomography (CBCT) scans, taken within 72 hours and 3 months after extraction, to measure changes in ridge height and width, and buccal and lingual plate thicknesses. Changes in keratinized tissue width were recorded. Three-arm analyses were performed using historic data from a previous randomized controlled trial by the same study group, in which 20 molar sites received a collagen wound dressing alone (control) and 20 received ridge preservation with freeze-dried bone allograft and a dense polytetrafluoroethylene membrane (test 1) using the same methodology. RESULTS: There was a statistically significant difference in mean buccal ridge height changes between the control group (2.6 ± 2.06 mm) and test 2 group (1.55 ± 0.93 mm) but no difference in ridge and keratinized tissue width changes between groups. No correlation was found between buccal plate thickness and ridge width change. CONCLUSION: Freeze-dried bone allograft with collagen wound dressing as a barrier was used successfully for ridge preservation in intact molar extraction sites (< 50% bone loss) and can be considered as a treatment alternative to freeze-dried bone allograft with a dense polytetrafluoroethylene membrane.

Original languageEnglish (US)
Pages (from-to)1202-1212
Number of pages11
JournalThe International journal of oral & maxillofacial implants
Volume34
Issue number5
DOIs
StatePublished - Sep 1 2019

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Bandages
Allografts
Arm
Collagen
Bone and Bones
Cheek
Wounds and Injuries
Polytetrafluoroethylene
Membranes
Tooth Extraction
Cone-Beam Computed Tomography
Tongue
Randomized Controlled Trials
Control Groups

ASJC Scopus subject areas

  • Oral Surgery

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Healing at Molar Extraction Sites Using Freeze-Dried Bone Allograft and Collagen Wound Dressing : Case Series and Three-Arm Analyses. / Al Harthi, Shaimaa M.; Prihoda, Thomas J.; Mealey, Brian L.; Lasho, David J; Noujeim, Marcel E; Huynh-ba, Guy.

In: The International journal of oral & maxillofacial implants, Vol. 34, No. 5, 01.09.2019, p. 1202-1212.

Research output: Contribution to journalArticle

Al Harthi, Shaimaa M. ; Prihoda, Thomas J. ; Mealey, Brian L. ; Lasho, David J ; Noujeim, Marcel E ; Huynh-ba, Guy. / Healing at Molar Extraction Sites Using Freeze-Dried Bone Allograft and Collagen Wound Dressing : Case Series and Three-Arm Analyses. In: The International journal of oral & maxillofacial implants. 2019 ; Vol. 34, No. 5. pp. 1202-1212.
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abstract = "PURPOSE: Ridge preservation limits dimensional changes after tooth extraction. However, it is still unclear if using a membrane may be advantageous over a collagen wound dressing. Therefore, the goal of this report was to evaluate the outcomes of ridge preservation using freeze-dried bone allograft with a collagen wound dressing. MATERIALS AND METHODS: This study included 21 patients who had one molar extracted, and the site received ridge preservation using freeze-dried bone allograft and a collagen wound dressing (test 2 group). Patients had two standardized cone beam computed tomography (CBCT) scans, taken within 72 hours and 3 months after extraction, to measure changes in ridge height and width, and buccal and lingual plate thicknesses. Changes in keratinized tissue width were recorded. Three-arm analyses were performed using historic data from a previous randomized controlled trial by the same study group, in which 20 molar sites received a collagen wound dressing alone (control) and 20 received ridge preservation with freeze-dried bone allograft and a dense polytetrafluoroethylene membrane (test 1) using the same methodology. RESULTS: There was a statistically significant difference in mean buccal ridge height changes between the control group (2.6 ± 2.06 mm) and test 2 group (1.55 ± 0.93 mm) but no difference in ridge and keratinized tissue width changes between groups. No correlation was found between buccal plate thickness and ridge width change. CONCLUSION: Freeze-dried bone allograft with collagen wound dressing as a barrier was used successfully for ridge preservation in intact molar extraction sites (< 50{\%} bone loss) and can be considered as a treatment alternative to freeze-dried bone allograft with a dense polytetrafluoroethylene membrane.",
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N2 - PURPOSE: Ridge preservation limits dimensional changes after tooth extraction. However, it is still unclear if using a membrane may be advantageous over a collagen wound dressing. Therefore, the goal of this report was to evaluate the outcomes of ridge preservation using freeze-dried bone allograft with a collagen wound dressing. MATERIALS AND METHODS: This study included 21 patients who had one molar extracted, and the site received ridge preservation using freeze-dried bone allograft and a collagen wound dressing (test 2 group). Patients had two standardized cone beam computed tomography (CBCT) scans, taken within 72 hours and 3 months after extraction, to measure changes in ridge height and width, and buccal and lingual plate thicknesses. Changes in keratinized tissue width were recorded. Three-arm analyses were performed using historic data from a previous randomized controlled trial by the same study group, in which 20 molar sites received a collagen wound dressing alone (control) and 20 received ridge preservation with freeze-dried bone allograft and a dense polytetrafluoroethylene membrane (test 1) using the same methodology. RESULTS: There was a statistically significant difference in mean buccal ridge height changes between the control group (2.6 ± 2.06 mm) and test 2 group (1.55 ± 0.93 mm) but no difference in ridge and keratinized tissue width changes between groups. No correlation was found between buccal plate thickness and ridge width change. CONCLUSION: Freeze-dried bone allograft with collagen wound dressing as a barrier was used successfully for ridge preservation in intact molar extraction sites (< 50% bone loss) and can be considered as a treatment alternative to freeze-dried bone allograft with a dense polytetrafluoroethylene membrane.

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