Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.
|Original language||English (US)|
|State||Published - Nov 12 2001|
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Cell Biology