Having a BLAST with bioinformatics (and avoiding BLAST phemy)

A. Pertsemlidis, J. W. Fondon

Research output: Contribution to journalShort surveypeer-review

72 Scopus citations


Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.

Original languageEnglish (US)
Article number2002
Pages (from-to)2002.1-2002.10
JournalGenome biology
Issue number10
StatePublished - Nov 12 2001
Externally publishedYes

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology


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