Handling of water and electrolytes by rabbit parotid and submaxillary glands

J. A. Mangos, N. R. McSherry, K. Irwin, R. Hong

Research output: Chapter in Book/Report/Conference proceedingChapter

22 Citations (Scopus)

Abstract

The secretory mechanisms and transductal fluxes of monovalent ions and water in the rabbit parotid and submaxillary glands were investigated by using micropuncture, microperfusion, and microanalytic techniques. The primary secretory fluid obtained from the intercalated ducts of both glands was hypertonic to plasma and had the following composition: parotid: [Na], 159.7 ± 8.4; [K], 3.1 ± 1.4 mEq/liter; [Cl], 131.6 ± 6.9 mEq/liter, submaxillary: [Na], 153.0 ± 7.2; [K], 11.5 ± 3.2; [Cl], 128.1 ± 5.7 mEq/liter. The [HCO3] was measured indirectly and was 27.8 ± 3.7 in the parotid and 26.3 ± 4.1 mEq/liter in the submaxillary. The excretory ducts showed low permeability to water in the presence of strong lumen to interstitium osmotic gradients. The net transductal fluxes of Na and Cl (efflux) in the rabbit parotid were 8.37 ± 1.05 and 7.44 ± 1.55 μEq/min.g wet gland tissue while the fluxes of K (influx) varied from 0.01 to 0.20 μEq/min.g wet gland tissue at different secretory flow rates. In the submaxillary ducts, the transductal fluxes of ions were of higher capacity than in the parotid, and steady state concentrations appeared to be the only limiting factor for continuing transductal transport of ions.

Original languageEnglish (US)
Title of host publicationAmerican Journal of Physiology
Pages450-455
Number of pages6
Volume225
Edition2
StatePublished - 1973
Externally publishedYes

Fingerprint

Submandibular Gland
Parotid Gland
Electrolytes
Secretory Rate
Ions
Rabbits
Water
Ion Transport
Punctures
Permeability

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mangos, J. A., McSherry, N. R., Irwin, K., & Hong, R. (1973). Handling of water and electrolytes by rabbit parotid and submaxillary glands. In American Journal of Physiology (2 ed., Vol. 225, pp. 450-455)

Handling of water and electrolytes by rabbit parotid and submaxillary glands. / Mangos, J. A.; McSherry, N. R.; Irwin, K.; Hong, R.

American Journal of Physiology. Vol. 225 2. ed. 1973. p. 450-455.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mangos, JA, McSherry, NR, Irwin, K & Hong, R 1973, Handling of water and electrolytes by rabbit parotid and submaxillary glands. in American Journal of Physiology. 2 edn, vol. 225, pp. 450-455.
Mangos JA, McSherry NR, Irwin K, Hong R. Handling of water and electrolytes by rabbit parotid and submaxillary glands. In American Journal of Physiology. 2 ed. Vol. 225. 1973. p. 450-455
Mangos, J. A. ; McSherry, N. R. ; Irwin, K. ; Hong, R. / Handling of water and electrolytes by rabbit parotid and submaxillary glands. American Journal of Physiology. Vol. 225 2. ed. 1973. pp. 450-455
@inbook{dea74271d7374fc1a6eac88799f3cba8,
title = "Handling of water and electrolytes by rabbit parotid and submaxillary glands",
abstract = "The secretory mechanisms and transductal fluxes of monovalent ions and water in the rabbit parotid and submaxillary glands were investigated by using micropuncture, microperfusion, and microanalytic techniques. The primary secretory fluid obtained from the intercalated ducts of both glands was hypertonic to plasma and had the following composition: parotid: [Na], 159.7 ± 8.4; [K], 3.1 ± 1.4 mEq/liter; [Cl], 131.6 ± 6.9 mEq/liter, submaxillary: [Na], 153.0 ± 7.2; [K], 11.5 ± 3.2; [Cl], 128.1 ± 5.7 mEq/liter. The [HCO3] was measured indirectly and was 27.8 ± 3.7 in the parotid and 26.3 ± 4.1 mEq/liter in the submaxillary. The excretory ducts showed low permeability to water in the presence of strong lumen to interstitium osmotic gradients. The net transductal fluxes of Na and Cl (efflux) in the rabbit parotid were 8.37 ± 1.05 and 7.44 ± 1.55 μEq/min.g wet gland tissue while the fluxes of K (influx) varied from 0.01 to 0.20 μEq/min.g wet gland tissue at different secretory flow rates. In the submaxillary ducts, the transductal fluxes of ions were of higher capacity than in the parotid, and steady state concentrations appeared to be the only limiting factor for continuing transductal transport of ions.",
author = "Mangos, {J. A.} and McSherry, {N. R.} and K. Irwin and R. Hong",
year = "1973",
language = "English (US)",
volume = "225",
pages = "450--455",
booktitle = "American Journal of Physiology",
edition = "2",

}

TY - CHAP

T1 - Handling of water and electrolytes by rabbit parotid and submaxillary glands

AU - Mangos, J. A.

AU - McSherry, N. R.

AU - Irwin, K.

AU - Hong, R.

PY - 1973

Y1 - 1973

N2 - The secretory mechanisms and transductal fluxes of monovalent ions and water in the rabbit parotid and submaxillary glands were investigated by using micropuncture, microperfusion, and microanalytic techniques. The primary secretory fluid obtained from the intercalated ducts of both glands was hypertonic to plasma and had the following composition: parotid: [Na], 159.7 ± 8.4; [K], 3.1 ± 1.4 mEq/liter; [Cl], 131.6 ± 6.9 mEq/liter, submaxillary: [Na], 153.0 ± 7.2; [K], 11.5 ± 3.2; [Cl], 128.1 ± 5.7 mEq/liter. The [HCO3] was measured indirectly and was 27.8 ± 3.7 in the parotid and 26.3 ± 4.1 mEq/liter in the submaxillary. The excretory ducts showed low permeability to water in the presence of strong lumen to interstitium osmotic gradients. The net transductal fluxes of Na and Cl (efflux) in the rabbit parotid were 8.37 ± 1.05 and 7.44 ± 1.55 μEq/min.g wet gland tissue while the fluxes of K (influx) varied from 0.01 to 0.20 μEq/min.g wet gland tissue at different secretory flow rates. In the submaxillary ducts, the transductal fluxes of ions were of higher capacity than in the parotid, and steady state concentrations appeared to be the only limiting factor for continuing transductal transport of ions.

AB - The secretory mechanisms and transductal fluxes of monovalent ions and water in the rabbit parotid and submaxillary glands were investigated by using micropuncture, microperfusion, and microanalytic techniques. The primary secretory fluid obtained from the intercalated ducts of both glands was hypertonic to plasma and had the following composition: parotid: [Na], 159.7 ± 8.4; [K], 3.1 ± 1.4 mEq/liter; [Cl], 131.6 ± 6.9 mEq/liter, submaxillary: [Na], 153.0 ± 7.2; [K], 11.5 ± 3.2; [Cl], 128.1 ± 5.7 mEq/liter. The [HCO3] was measured indirectly and was 27.8 ± 3.7 in the parotid and 26.3 ± 4.1 mEq/liter in the submaxillary. The excretory ducts showed low permeability to water in the presence of strong lumen to interstitium osmotic gradients. The net transductal fluxes of Na and Cl (efflux) in the rabbit parotid were 8.37 ± 1.05 and 7.44 ± 1.55 μEq/min.g wet gland tissue while the fluxes of K (influx) varied from 0.01 to 0.20 μEq/min.g wet gland tissue at different secretory flow rates. In the submaxillary ducts, the transductal fluxes of ions were of higher capacity than in the parotid, and steady state concentrations appeared to be the only limiting factor for continuing transductal transport of ions.

UR - http://www.scopus.com/inward/record.url?scp=0015881297&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015881297&partnerID=8YFLogxK

M3 - Chapter

C2 - 4722409

AN - SCOPUS:0015881297

VL - 225

SP - 450

EP - 455

BT - American Journal of Physiology

ER -