Guidewire electrosurgery-assisted trans-septal puncture

Jaffar M. Khan, Toby Rogers, Marvin H. Eng, Robert J. Lederman, Adam B. Greenbaum

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objectives: Electrifying a coronary guidewire may be a simple escalation strategy when trans-septal needle puncture is unsuccessful. Background: Radiofrequency energy to facilitate trans-septal puncture through a dedicated device is costly and directly through a trans-septal needle may be less safe. Our technique overcomes these limitations. Methods: The technique was used in patients when trans-septal needle penetration failed despite excessive force or tenting of the atrial septum. A coronary guidewire, connected to an electrosurgery pencil, was advanced through the trans-septal needle, dilator, and sheath to perforate the interatrial septum during a short burst of radiofrequency energy. With the guidewire tip no longer “active,” the dilator and sheath were advanced safely over the wire into the left atrium. In posthoc validation, radiofrequency assisted Brockenbrough needle and coronary guidewire punctures were made in freshly explanted pig hearts and compared under microscopy. Results: Eight patients who required trans-septal access for structural intervention were escalated to a guidewire electrosurgery strategy. Six patients had thickened fibrotic septum and two had prior surgical patch repair. Crossing was successful in all patients with no procedure related complications. The size of punctures (1.11 ± 0.40 mm vs 0.37 ± 0.08 mm, P =.009) and blanched penumbra (3.62 ± 1.23 mm vs 0.72 ± 0.29 mm, P =.003) in pig atrial septum were larger with an electrified needle than electrified guidewire. The hole generated by the electrified guidewire was smaller than by the nonelectrified needle. Conclusions: When conventional trans-septal puncture fails, a coronary guidewire can be used to deliver brief radiofrequency energy safely and effectively. This technique is inexpensive and accessible to operators.

Original languageEnglish (US)
Pages (from-to)1164-1170
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Issue number6
StatePublished - May 1 2018


  • electrophysiology
  • left atrial appendage closure
  • mitral valve disease
  • percutaneous intervention
  • structural heart disease intervention
  • trans-septal catheterization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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