Growth of a water strain of Leptospira in synthetic media

R. C. Henneberry, J. B. Baseman, C. D. Cox

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Pertinent parameters of growth of a water strain of Leptospira in synthetic media are described. Growth rates as a function of aeration, temperature, and substrate concentration were determined. Evidence is presented for the production of acetate and CO2 from long-chain fatty acids. A marked drop in pH was shown to result from the accumulation of acetate during growth in synthetic medium. Growth was initiated at pH values from 5.2 to 7.7. An absolute CO2 requirement for initiation of growth was demonstrated. Growth is also described with acetate as the sole carbon and energy source, demonstrating that leptospires are capable of fatty acid synthesis.

Original languageEnglish (US)
Pages (from-to)489-501
Number of pages13
JournalAntonie van Leeuwenhoek
Issue number1
StatePublished - Dec 1970
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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