Growth competition between Candida dubliniensis and Candida albicans under broth and biofilm growing conditions

W. R. Kirkpatrick, J. L. Lopez-Ribot, R. K. Mcatee, T. F. Patterson

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Seven isolates each of Candida albicans and Candida dubliniensis were paired (11 pairs) and examined for competitive interaction. Equal numbers of CFU of each competitor were inoculated into Sabouraud dextrose broth and incubated at 37°C with vigorous shaking under conditions favorable to either broth or biofilm growth. Surviving proportions of each competitor were calculated from the broth culture at 24 and 96 h and the biofilm culture at 96 h, with species differentiation done on CHROMagar Candida medium. C. albicans had a competitive advantage over C. dubliniensis in broth culture and under biofilm growing conditions; however, with the presence of a supporting structure for biofilm formation, C. dubliniensis was able to better withstand the competitive pressures from C. albicans.

Original languageEnglish (US)
Pages (from-to)902-904
Number of pages3
JournalJournal of clinical microbiology
Volume38
Issue number2
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Microbiology (medical)

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