Glycogen phosphorylase: A novel biomarker in doxorubicin-induced cardiac injury

Yueming Zhu; David Gius

doi:10.1158/1078-0432.CCR-17-3276

Glycogen phosphorylase: A novel biomarker in doxorubicin-induced cardiac injury

Yueming Zhu, David Gius

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Extracellular vesicles containing glycogen phosphorylase, brain/heart (PYGB) have been demonstrated as a sensitive biomarker for normal cardiac injuries for patients after chemotherapy. Oxidative stress was suggested to be the mechanism behind the chemotherapy-induced tissue damage and augmented with mitochondrial antioxidant could be an effective means of early intervention.

Original language	English (US)
Pages (from-to)	1516-1517
Number of pages	2
Journal	Clinical Cancer Research
Volume	24
Issue number	7
DOIs	https://doi.org/10.1158/1078-0432.CCR-17-3276
State	Published - Apr 1 2018
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1158/1078-0432.CCR-17-3276

Cite this

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title = "Glycogen phosphorylase: A novel biomarker in doxorubicin-induced cardiac injury",

abstract = "Extracellular vesicles containing glycogen phosphorylase, brain/heart (PYGB) have been demonstrated as a sensitive biomarker for normal cardiac injuries for patients after chemotherapy. Oxidative stress was suggested to be the mechanism behind the chemotherapy-induced tissue damage and augmented with mitochondrial antioxidant could be an effective means of early intervention.",

author = "Yueming Zhu and David Gius",

note = "Publisher Copyright: {\textcopyright} 2018 American Association for Cancer Research.",

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AU - Gius, David

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AB - Extracellular vesicles containing glycogen phosphorylase, brain/heart (PYGB) have been demonstrated as a sensitive biomarker for normal cardiac injuries for patients after chemotherapy. Oxidative stress was suggested to be the mechanism behind the chemotherapy-induced tissue damage and augmented with mitochondrial antioxidant could be an effective means of early intervention.

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Glycogen phosphorylase: A novel biomarker in doxorubicin-induced cardiac injury

Abstract

ASJC Scopus subject areas

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