TY - JOUR
T1 - Glycemic control with regular versus lispro insulin sliding scales in hospitalized Type 2 diabetics
AU - Alfonso, Abel
AU - Koops, Maureen K.
AU - Mong, Dennis P.
AU - Vigersky, Robert A.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2006/5
Y1 - 2006/5
N2 - Purpose: The aim of this study was to compare glycemic control with either regular or lispro insulin sliding scales in hospitalized Type 2 diabetics who were not using insulin as outpatients. Methods: Forty-three patients with Type 2 diabetes, who were taking oral agents only, were admitted to a medical inpatient service and randomized to receive either regular or lispro insulin sliding scale. Oral agents for diabetes were held upon admission and patients were followed throughout their hospital stay. Results: There was no significant difference (P>.05) between the average finger-stick blood glucose (FSBG) in the regular insulin group (157.78±40.16 mg/dl) and the lispro insulin group (152.04±27.71 mg/dl). No significant difference was found between the daily dose of insulin (regular, 5.83±5.01 units; lispro, 4.27±3.40 units), total amount of insulin used during hospitalization (regular, 11.87±10.78 units; lispro, 12.77±14.39 units), glucose excursion (regular, 110.13±25.86 mg/dl; lispro, 106.77±52.65 mg/dl), or length of hospital stay (regular, 2.33±1.23 days; lispro, 2.69±1.59 days). Conclusion: No significant difference in glycemic control was found in hospitalized Type 2 diabetic patients who received either regular or lispro insulin sliding scales. Both insulin sliding scales used in this study are inadequate to achieve current recommended glycemic targets in this patient population, when used as the only inpatient treatment for diabetes.
AB - Purpose: The aim of this study was to compare glycemic control with either regular or lispro insulin sliding scales in hospitalized Type 2 diabetics who were not using insulin as outpatients. Methods: Forty-three patients with Type 2 diabetes, who were taking oral agents only, were admitted to a medical inpatient service and randomized to receive either regular or lispro insulin sliding scale. Oral agents for diabetes were held upon admission and patients were followed throughout their hospital stay. Results: There was no significant difference (P>.05) between the average finger-stick blood glucose (FSBG) in the regular insulin group (157.78±40.16 mg/dl) and the lispro insulin group (152.04±27.71 mg/dl). No significant difference was found between the daily dose of insulin (regular, 5.83±5.01 units; lispro, 4.27±3.40 units), total amount of insulin used during hospitalization (regular, 11.87±10.78 units; lispro, 12.77±14.39 units), glucose excursion (regular, 110.13±25.86 mg/dl; lispro, 106.77±52.65 mg/dl), or length of hospital stay (regular, 2.33±1.23 days; lispro, 2.69±1.59 days). Conclusion: No significant difference in glycemic control was found in hospitalized Type 2 diabetic patients who received either regular or lispro insulin sliding scales. Both insulin sliding scales used in this study are inadequate to achieve current recommended glycemic targets in this patient population, when used as the only inpatient treatment for diabetes.
KW - Insulin
KW - Lispro
KW - Regular
KW - Sliding scales
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U2 - 10.1016/j.jdiacomp.2005.06.009
DO - 10.1016/j.jdiacomp.2005.06.009
M3 - Article
C2 - 16632234
AN - SCOPUS:33646047699
VL - 20
SP - 153
EP - 157
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
SN - 1056-8727
IS - 3
ER -