Global left ventricular longitudinal strain is associated with decreased melatonin levels in patients with acute myocardial infarction: A two-dimensional speckle tracking study

Alberto Dominguez-Rodriguez, Pedro Abreu-Gonzalez, Eduardo Arroyo-Ucar, Pablo Avanzas, Russel J. Reiter

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Low circulating melatonin levels predict poor outcome in patients with ST-segment elevation myocardial infarction (STEMI). In the present study, we investigated whether a relationship between myocardial deformation in parameters measured by echocardiography and circulating melatonin level exists. We prospectively included 112 patients with STEMI who performed echocardiography and simultaneous measurement of serum melatonin, during the light period within 72 h of admission. We found a negative correlation between circulating melatonin levels and global longitudinal strain (p = 0.006, r = -0.33). In conclusion, melatonin levels have a correlation with two-dimensional speckle tracking in patients with STEMI.

Original languageEnglish (US)
Pages (from-to)310-313
Number of pages4
JournalBiomarkers
Volume18
Issue number4
DOIs
StatePublished - May 29 2013

Keywords

  • Echocardiography
  • Melatonin
  • ST-segment elevation myocardial infarction
  • Speckle tracking

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Health, Toxicology and Mutagenesis

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