@inbook{f425627495d3498b9b5dbac3d7e69cd2,
title = "Genome-wide methylation profiling in archival formalin-fixed paraffin-embedded tissue samples",
abstract = "New technologies allow for genome-scale measurement of DNA methylation. In an effort to increase the clinical utility of DNA methylation as a biomarker, we have adapted a commercial bisulfite epigenotyping assay for genome-wide methylation profiling in archival formalin-fixed paraffin-embedded pathology specimens. This chapter takes the reader step by step through a biomarker discovery experiment to identify phenotype-correlated DNA methylation signatures in routine pathology specimens.",
keywords = "Biomarker, DNA methylation, Epigenetics, FFPE, Pathology",
author = "Killian, \{J. Keith\} and Walker, \{Robert L.\} and Sven Bilke and Yidong Chen and Sean Davis and Robert Cornelison and Smith, \{William I.\} and Meltzer, \{Paul S.\}",
year = "2012",
doi = "10.1007/978-1-60327-216-2\_8",
language = "English (US)",
isbn = "9781603272155",
series = "Methods in Molecular Biology",
pages = "107--118",
editor = "Virginia Espina and Lance Liotta",
booktitle = "Molecular Profiling",
}