TY - JOUR
T1 - Genome mining for human cancer genes
T2 - Wherefore art thou?
AU - Boyer, Thomas G.
AU - Chen, Phang Lang
AU - Lee, Wen Hwa
PY - 2001
Y1 - 2001
N2 - In an initial data-mining effort, the draft human genome was searched to find paralogs of known tumor suppressor genes, and for gene arrangements, which are typical of oncogenes, in cancer cells. The results were disappointing, indicating that although knowledge of the human genome will undoubtedly be of great help, other approaches to identify new oncogenes are needed.
AB - In an initial data-mining effort, the draft human genome was searched to find paralogs of known tumor suppressor genes, and for gene arrangements, which are typical of oncogenes, in cancer cells. The results were disappointing, indicating that although knowledge of the human genome will undoubtedly be of great help, other approaches to identify new oncogenes are needed.
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UR - http://www.scopus.com/inward/citedby.url?scp=0034851366&partnerID=8YFLogxK
U2 - 10.1016/S1471-4914(01)01990-6
DO - 10.1016/S1471-4914(01)01990-6
M3 - Review article
C2 - 11325617
AN - SCOPUS:0034851366
VL - 7
SP - 187
EP - 189
JO - Trends in Molecular Medicine
JF - Trends in Molecular Medicine
SN - 1471-4914
IS - 5
ER -