Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014

Mary B. Daly; Robert Pilarski; Jennifer E. Axilbund; Saundra S. Buys; Beth Crawford; Susan Friedman; Judy E. Garber; Carolyn Horton; Virginia Kaklamani; Catherine Klein; Wendy Kohlmann; Allison Kurian; Jennifer Litton; Lisa Madlensky; P. Kelly Marcom; Sofia D. Merajver; Kenneth Offit; Tuya Pal; Boris Pasche; Gwen Reiser; Kristen Mahoney Shannon; Elizabeth Swisher; Nicoleta C. Voian; Jeffrey N. Weitzel; Alison Whelan; Georgia L. Wiesner; Mary A. Dwyer; Rashmi Kumar

doi:10.6004/jnccn.2014.0127

Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014

Mary B. Daly, Robert Pilarski, Jennifer E. Axilbund, Saundra S. Buys, Beth Crawford, Susan Friedman, Judy E. Garber, Carolyn Horton, Virginia Kaklamani, Catherine Klein, Wendy Kohlmann, Allison Kurian, Jennifer Litton, Lisa Madlensky, P. Kelly Marcom, Sofia D. Merajver, Kenneth Offit, Tuya Pal, Boris Pasche, Gwen ReiserKristen Mahoney Shannon, Elizabeth Swisher, Nicoleta C. Voian, Jeffrey N. Weitzel, Alison Whelan, Georgia L. Wiesner, Mary A. Dwyer, Rashmi Kumar

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97 Scopus citations

Abstract

During the past few years, several genetic aberrations that may contribute to increased risks for development of breast and/ or ovarian cancers have been identified. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian focus specifically on the assessment of genetic mutations in BRCA1/BRCA2, TP53, and PTEN, and recommend approaches to genetic testing/counseling and management strategies in individuals with these mutations. This portion of the NCCN Guidelines includes recommendations regarding diagnostic criteria and management of patients with Cowden Syndrome/ PTEN hamartoma tumor syndrome.

Original language	English (US)
Pages (from-to)	1326-1338
Number of pages	13
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	12
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2014.0127
State	Published - Sep 1 2014
Externally published	Yes

ASJC Scopus subject areas

Oncology

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Daly, M. B., Pilarski, R., Axilbund, J. E., Buys, S. S., Crawford, B., Friedman, S., Garber, J. E., Horton, C., Kaklamani, V., Klein, C., Kohlmann, W., Kurian, A., Litton, J., Madlensky, L., Marcom, P. K., Merajver, S. D., Offit, K., Pal, T., Pasche, B., ... Kumar, R. (2014). Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014. JNCCN Journal of the National Comprehensive Cancer Network, 12(9), 1326-1338. https://doi.org/10.6004/jnccn.2014.0127

Daly, MB, Pilarski, R, Axilbund, JE, Buys, SS, Crawford, B, Friedman, S, Garber, JE, Horton, C, Kaklamani, V, Klein, C, Kohlmann, W, Kurian, A, Litton, J, Madlensky, L, Marcom, PK, Merajver, SD, Offit, K, Pal, T, Pasche, B, Reiser, G, Shannon, KM, Swisher, E, Voian, NC, Weitzel, JN, Whelan, A, Wiesner, GL, Dwyer, MA & Kumar, R 2014, 'Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014', JNCCN Journal of the National Comprehensive Cancer Network, vol. 12, no. 9, pp. 1326-1338. https://doi.org/10.6004/jnccn.2014.0127

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abstract = "During the past few years, several genetic aberrations that may contribute to increased risks for development of breast and/ or ovarian cancers have been identified. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian focus specifically on the assessment of genetic mutations in BRCA1/BRCA2, TP53, and PTEN, and recommend approaches to genetic testing/counseling and management strategies in individuals with these mutations. This portion of the NCCN Guidelines includes recommendations regarding diagnostic criteria and management of patients with Cowden Syndrome/ PTEN hamartoma tumor syndrome.",

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AU - Daly, Mary B.

AU - Pilarski, Robert

AU - Axilbund, Jennifer E.

AU - Buys, Saundra S.

AU - Crawford, Beth

AU - Friedman, Susan

AU - Garber, Judy E.

AU - Horton, Carolyn

AU - Kaklamani, Virginia

AU - Klein, Catherine

AU - Kohlmann, Wendy

AU - Kurian, Allison

AU - Litton, Jennifer

AU - Madlensky, Lisa

AU - Marcom, P. Kelly

AU - Merajver, Sofia D.

AU - Offit, Kenneth

AU - Pal, Tuya

AU - Pasche, Boris

AU - Reiser, Gwen

AU - Shannon, Kristen Mahoney

AU - Swisher, Elizabeth

AU - Voian, Nicoleta C.

AU - Weitzel, Jeffrey N.

AU - Whelan, Alison

AU - Wiesner, Georgia L.

AU - Dwyer, Mary A.

AU - Kumar, Rashmi

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Genetic/familial high-risk assessment: Breast and ovarian, version 1.2014

Abstract

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