Genetic variation of Venezuelan equine encephalitis virus strains of the ID variety in Colombia

R. Rico-Hesse, J. T. Roehrig, D. W. Trent, R. W. Dickerman

    Research output: Contribution to journalArticle

    22 Scopus citations

    Abstract

    To determine the degree of genetic variation within one serologic group of Venezuelan equine encephalitis virus and the relatedness of viruses with different epidemiologic backgrounds isolated within the same country, virion RNA from 16 isolates belonging to subtype I were compared by RNase T1 oligonucleotide fingerprinting. RNA fingerprints of 12 enzootic isolates showed a large degree of heterogeneity, even though they were serologically indistinguishable. A reference enzootic strain from Colombia showed more genetic relatedness to three epizootic strains isolated in the same country, than to its own serogroup prototype strain isolated in Panama. Thus, genetic relatedness within Venezuelan equine encephalitis strains in Colombia seems to be a function of geography rather than epidemiology.

    Original languageEnglish (US)
    Pages (from-to)195-204
    Number of pages10
    JournalAmerican Journal of Tropical Medicine and Hygiene
    Volume38
    Issue number1
    DOIs
    StatePublished - Jan 1 1988

    ASJC Scopus subject areas

    • Parasitology
    • Virology
    • Infectious Diseases

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