Abstract
A genetic polymorphism for the soluble isozyme (MDH-A2) of malate dehydrogenase (L-malate: NAD+ oxidoreductase; EC 1.1.1.37) was found in a Townsville-Inkerman population of short-nosed bandicoots, 1. macrourus. The enzyme seems to be inherited in a normal autosomal codominant manner. The gene frequencies for the MDH-A and MDH-A′ alleles were 0·82 and 0·18 respectively. The genotypic frequencies indicated that the population was in Hardy-Weinberg equilibrium. None of 22 pouch young from seven litters expressed a phenotype inconsistent with its mother’s genotype, assuming autosomal co dominance. Other populations of I. macrourus and of the long-nosed bandicoot (Perameles nasuta) exhibited only the MDH-A allele. Homologous relationships of bandicoot MDH-A2 and MDH-B2 isozymes to those of other vertebrates were established by immunochemical studies.
Original language | English (US) |
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Pages (from-to) | 677-682 |
Number of pages | 6 |
Journal | Australian Journal of Biological Sciences |
Volume | 27 |
Issue number | 6 |
DOIs | |
State | Published - 1974 |
ASJC Scopus subject areas
- Biotechnology
- Reproductive Medicine
- Animal Science and Zoology
- Molecular Biology
- Materials Science(all)
- Genetics
- Endocrinology
- Developmental Biology