Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.

P. S. Gill; S. M. Chahal; J. Blangero; R. S. Corruccini; I. J. Bansal; S. S. Kaul; V. Bhalla

Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.

P. S. Gill, S. M. Chahal, J. Blangero, R. S. Corruccini, I. J. Bansal, S. S. Kaul, V. Bhalla

Research output: Contribution to journal › Article › peer-review

Abstract

Studies on monozygotic (MZ) twins and admixed populations show that the predisposition to non-insulin-dependent diabetes mellitus has a large genetic component. We have examined the distribution of some genetic polymorphisms (ABO, GLO, ESD, AK, ACPA, and GPI) in control and diabetic Punjabis from north India. The distribution of various genetic markers indicate that the differences between the control and diabetic samples are statistically not significant. Moreover, a contingency chi-square analysis over all loci suggests nonsignificant genetic differentiation (p = 0.50) between the Punjabi samples.

Original language	English (US)
Pages (from-to)	549-553
Number of pages	5
Journal	Human biology; an international record of research
Volume	63
Issue number	4
State	Published - Aug 1991

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Genetics(clinical)

Cite this

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title = "Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.",

abstract = "Studies on monozygotic (MZ) twins and admixed populations show that the predisposition to non-insulin-dependent diabetes mellitus has a large genetic component. We have examined the distribution of some genetic polymorphisms (ABO, GLO, ESD, AK, ACPA, and GPI) in control and diabetic Punjabis from north India. The distribution of various genetic markers indicate that the differences between the control and diabetic samples are statistically not significant. Moreover, a contingency chi-square analysis over all loci suggests nonsignificant genetic differentiation (p = 0.50) between the Punjabi samples.",

author = "Gill, {P. S.} and Chahal, {S. M.} and J. Blangero and Corruccini, {R. S.} and Bansal, {I. J.} and Kaul, {S. S.} and V. Bhalla",

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AU - Chahal, S. M.

AU - Blangero, J.

AU - Corruccini, R. S.

AU - Bansal, I. J.

AU - Kaul, S. S.

AU - Bhalla, V.

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AB - Studies on monozygotic (MZ) twins and admixed populations show that the predisposition to non-insulin-dependent diabetes mellitus has a large genetic component. We have examined the distribution of some genetic polymorphisms (ABO, GLO, ESD, AK, ACPA, and GPI) in control and diabetic Punjabis from north India. The distribution of various genetic markers indicate that the differences between the control and diabetic samples are statistically not significant. Moreover, a contingency chi-square analysis over all loci suggests nonsignificant genetic differentiation (p = 0.50) between the Punjabi samples.

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Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.

Abstract

ASJC Scopus subject areas

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