Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.

P. S. Gill, S. M. Chahal, J. Blangero, R. S. Corruccini, I. J. Bansal, S. S. Kaul, V. Bhalla

    Research output: Contribution to journalArticle

    2 Scopus citations

    Abstract

    Studies on monozygotic (MZ) twins and admixed populations show that the predisposition to non-insulin-dependent diabetes mellitus has a large genetic component. We have examined the distribution of some genetic polymorphisms (ABO, GLO, ESD, AK, ACPA, and GPI) in control and diabetic Punjabis from north India. The distribution of various genetic markers indicate that the differences between the control and diabetic samples are statistically not significant. Moreover, a contingency chi-square analysis over all loci suggests nonsignificant genetic differentiation (p = 0.50) between the Punjabi samples.

    Original languageEnglish (US)
    Pages (from-to)549-553
    Number of pages5
    JournalHuman biology; an international record of research
    Volume63
    Issue number4
    StatePublished - Aug 1991

    ASJC Scopus subject areas

    • Ecology, Evolution, Behavior and Systematics
    • Genetics
    • Genetics(clinical)

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    Gill, P. S., Chahal, S. M., Blangero, J., Corruccini, R. S., Bansal, I. J., Kaul, S. S., & Bhalla, V. (1991). Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis. Human biology; an international record of research, 63(4), 549-553.