Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.

P. S. Gill, S. M. Chahal, J. Blangero, R. S. Corruccini, I. J. Bansal, S. S. Kaul, V. Bhalla

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Studies on monozygotic (MZ) twins and admixed populations show that the predisposition to non-insulin-dependent diabetes mellitus has a large genetic component. We have examined the distribution of some genetic polymorphisms (ABO, GLO, ESD, AK, ACPA, and GPI) in control and diabetic Punjabis from north India. The distribution of various genetic markers indicate that the differences between the control and diabetic samples are statistically not significant. Moreover, a contingency chi-square analysis over all loci suggests nonsignificant genetic differentiation (p = 0.50) between the Punjabi samples.

Original languageEnglish (US)
Pages (from-to)549-553
Number of pages5
JournalHuman Biology
Volume63
Issue number4
StatePublished - Aug 1991
Externally publishedYes

Fingerprint

Molecular Epidemiology
Monozygotic Twins
diabetes
genetic marker
Genetic Polymorphisms
epidemiology
Genetic Markers
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
India
genetic markers
genetic differentiation
Population
polymorphism
genetic polymorphism
sampling
genetic variation
loci
distribution
analysis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Genetics(clinical)

Cite this

Gill, P. S., Chahal, S. M., Blangero, J., Corruccini, R. S., Bansal, I. J., Kaul, S. S., & Bhalla, V. (1991). Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis. Human Biology, 63(4), 549-553.

Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India : preliminary analyses of some genetic markers in Punjabis. / Gill, P. S.; Chahal, S. M.; Blangero, J.; Corruccini, R. S.; Bansal, I. J.; Kaul, S. S.; Bhalla, V.

In: Human Biology, Vol. 63, No. 4, 08.1991, p. 549-553.

Research output: Contribution to journalArticle

Gill, PS, Chahal, SM, Blangero, J, Corruccini, RS, Bansal, IJ, Kaul, SS & Bhalla, V 1991, 'Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India: preliminary analyses of some genetic markers in Punjabis.', Human Biology, vol. 63, no. 4, pp. 549-553.
Gill, P. S. ; Chahal, S. M. ; Blangero, J. ; Corruccini, R. S. ; Bansal, I. J. ; Kaul, S. S. ; Bhalla, V. / Genetic epidemiology of non-insulin-dependent diabetes mellitus in north India : preliminary analyses of some genetic markers in Punjabis. In: Human Biology. 1991 ; Vol. 63, No. 4. pp. 549-553.
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