Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo

Biochemistry, Genetics and Molecular Biology

• Haploinsufficiency 100%
• Mast Cell 100%
• Cell Fate 40%
• Melanocyte 40%
• Mouse 40%
• Receptor Tyrosine Kinase 20%
• Allele 20%
• Mutation 20%
• Phenotype 20%
• Wild Type 20%
• Cell Survival 20%
• Cell Proliferation 20%
• Solid 20%
• GTPase-activating Protein 20%
• Electric Potential 20%
• Cell Culture 20%
• Colony Formation 20%
• Mitogen-Activated Protein Kinase 20%
• Autosomal Dominant Inheritance 20%
• Biological Activity 20%
• Myeloid 20%
• Murine 20%
• Cell Lineage 20%
• Protein 20%
• Mutant 20%
• Genetics 20%
• Color 20%