Gene for parathyroid hormone-like peptide is on mouse chromosome 6

G. N. Hendy; A. Y. Sakaguchi; P. A. Lalley; L. Martinez; T. Yasuda; D. Banville; D. Goltzman

doi:10.1159/000132899

Gene for parathyroid hormone-like peptide is on mouse chromosome 6

G. N. Hendy, A. Y. Sakaguchi, P. A. Lalley, L. Martinez, T. Yasuda, D. Banville, D. Goltzman

Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

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Abstract

The single-copy parathyroid hormone-like peplide gene (Ptlilh) was assigned to mouse chromosome 6 using a rat PTHLH cDNA as hybridization probe in Southern blot analysis of DN As isolated from a panel of mouse x Chinese hamster cell hybrids. The mouse parathyroid hormone gene (Prh) has previously been assigned to mouse chromosome 7 and the PTHLH and PTH genes have also been shown to be on different chromosomes in human and rat. Therefore, despite significant amino-terminal sequence homology between the PTHLH and PTH peptides. as well as similarities in the structural organization of the human PTH LH and PTH genes, the genes encoding these peptides have discrete chromosomal locations in the mouse, rat, and man.

Original language	English (US)
Pages (from-to)	80-82
Number of pages	3
Journal	Cytogenetic and Genome Research
Volume	53
Issue number	2-3
DOIs	https://doi.org/10.1159/000132899
State	Published - 1990

ASJC Scopus subject areas

Molecular Biology
Genetics
Genetics(clinical)

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title = "Gene for parathyroid hormone-like peptide is on mouse chromosome 6",

abstract = "The single-copy parathyroid hormone-like peplide gene (Ptlilh) was assigned to mouse chromosome 6 using a rat PTHLH cDNA as hybridization probe in Southern blot analysis of DN As isolated from a panel of mouse x Chinese hamster cell hybrids. The mouse parathyroid hormone gene (Prh) has previously been assigned to mouse chromosome 7 and the PTHLH and PTH genes have also been shown to be on different chromosomes in human and rat. Therefore, despite significant amino-terminal sequence homology between the PTHLH and PTH peptides. as well as similarities in the structural organization of the human PTH LH and PTH genes, the genes encoding these peptides have discrete chromosomal locations in the mouse, rat, and man.",

author = "Hendy, {G. N.} and Sakaguchi, {A. Y.} and Lalley, {P. A.} and L. Martinez and T. Yasuda and D. Banville and D. Goltzman",

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T1 - Gene for parathyroid hormone-like peptide is on mouse chromosome 6

AU - Hendy, G. N.

AU - Sakaguchi, A. Y.

AU - Lalley, P. A.

AU - Martinez, L.

AU - Yasuda, T.

AU - Banville, D.

AU - Goltzman, D.

PY - 1990

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AB - The single-copy parathyroid hormone-like peplide gene (Ptlilh) was assigned to mouse chromosome 6 using a rat PTHLH cDNA as hybridization probe in Southern blot analysis of DN As isolated from a panel of mouse x Chinese hamster cell hybrids. The mouse parathyroid hormone gene (Prh) has previously been assigned to mouse chromosome 7 and the PTHLH and PTH genes have also been shown to be on different chromosomes in human and rat. Therefore, despite significant amino-terminal sequence homology between the PTHLH and PTH peptides. as well as similarities in the structural organization of the human PTH LH and PTH genes, the genes encoding these peptides have discrete chromosomal locations in the mouse, rat, and man.

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