Gastrointestinal Malacoplakia: Report of a Case and a Review of the Literature

IRWAN D. SANUSI, FERMIN O. TIO

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

A case of malacoplakia of the rectosigmoid colon in a nine‐year old girl was studied by light and electron microscopy. The gross appearance consisted of multiple polypoid lesions with characteristic dimpling or umbilication of the covering mucosa. Histologically the lesions were composed of mucosal and submucosal proliferation of histiocytes with the typical cytoplasmic inclusions known as Michaelis‐Gutmann bodies. Ultrastructurally these inclusions had a dense central calcified body and concentric alternating rings of light and dark zones. A review of the world literature of 16 previously reported cases of gastrointestinal malacoplakia is presented with emphasis on incidence, coexisting diseases and clinical diagnostic problems.

Original languageEnglish (US)
Pages (from-to)356-366
Number of pages11
JournalThe American journal of gastroenterology
Volume62
Issue number4
DOIs
StatePublished - Oct 1974
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint

Dive into the research topics of 'Gastrointestinal Malacoplakia: Report of a Case and a Review of the Literature'. Together they form a unique fingerprint.

Cite this