Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the Young International Society of Geriatric Oncology

Mark A. Baxter; Joana Marinho; Enrique Soto-Perez-de-Celis; Maria Grazia Rodriquenz; Sukeshi Patel Arora; Wendy Chan Wing Lok; Yung Yu Shih; Gabor Liposits; Shane O'Hanlon; Russell D. Petty

doi:10.1016/j.jgo.2021.09.006

Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the Young International Society of Geriatric Oncology

Mark A. Baxter, Joana Marinho, Enrique Soto-Perez-de-Celis, Maria Grazia Rodriquenz, Sukeshi Patel Arora, Wendy Chan Wing Lok, Yung Yu Shih, Gabor Liposits, Shane O'Hanlon, Russell D. Petty

Research output: Contribution to journal › Review article › peer-review

Abstract

Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.

Original language	English (US)
Pages (from-to)	7-19
Number of pages	13
Journal	Journal of Geriatric Oncology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/j.jgo.2021.09.006
State	Published - Jan 2022
Externally published	Yes

Keywords

Frailty
Gastroesophageal adenocarcinoma
Multi-disciplinary
Real-world
Toxicity

ASJC Scopus subject areas

Oncology
Geriatrics and Gerontology

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10.1016/j.jgo.2021.09.006

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Baxter, M. A., Marinho, J., Soto-Perez-de-Celis, E., Rodriquenz, M. G., Arora, S. P., Lok, W. C. W., Shih, Y. Y., Liposits, G., O'Hanlon, S., & Petty, R. D. (2022). Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the Young International Society of Geriatric Oncology. Journal of Geriatric Oncology, 13(1), 7-19. https://doi.org/10.1016/j.jgo.2021.09.006

Baxter, MA, Marinho, J, Soto-Perez-de-Celis, E, Rodriquenz, MG, Arora, SP, Lok, WCW, Shih, YY, Liposits, G, O'Hanlon, S & Petty, RD 2022, 'Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the Young International Society of Geriatric Oncology', Journal of Geriatric Oncology, vol. 13, no. 1, pp. 7-19. https://doi.org/10.1016/j.jgo.2021.09.006

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abstract = "Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.",

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year = "2022",

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doi = "10.1016/j.jgo.2021.09.006",

language = "English (US)",

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AU - Rodriquenz, Maria Grazia

AU - Arora, Sukeshi Patel

AU - Lok, Wendy Chan Wing

AU - Shih, Yung Yu

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AB - Gastroesophageal adenocarcinoma is a disease of older adults with very poor survival rates. Its incidence has risen dramatically across the world in recent decades. Current treatment approaches for older adults are based largely on extrapolated evidence from clinical trials conducted in younger and fitter participants than those more commonly encountered in clinical practice. Understanding how to apply available evidence to our patients in the clinic setting is essential given the high morbidity of both curative and palliative treatment. This review aims to use available data to inform the management of an older adult with gastroesophageal adenocarcinoma.

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Gastroesophageal adenocarcinoma in older adults: A comprehensive narrative review of management by the Young International Society of Geriatric Oncology

Abstract

Keywords

ASJC Scopus subject areas

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