Serum gastrin levels have been measured in a group of patients with extensive thermal injuries. They are not altered by burn injury nor do they correlate significantly with burn size, sepsis, or occurrence of gastroduodenal ulceration. These findings are consistent with previous acid secretory studies and suggests that Curling ulcer diathesis is determined primarily by defects in the barrier function of the gastric mucosa rather than by abnormal acid production.
|Original language||English (US)|
|Number of pages||3|
|Journal||Archives of Surgery|
|State||Published - Oct 1973|
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