Gastric tonometry: The role of mucosal pH measurement in the management of trauma

S. Morad Hameed, Stephen M. Cohn

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Effective management of hemorrhagic shock depends on titration of therapies against reliable resuscitation end points. Conventional clinical and laboratory indexes of shock are often slow to respond to progressive circulatory compromise. GI mucosal ischemia resulting from redistribution of blood flow may, however, precede uncompensated shock and may compound the initial hemorrhagic insult by touching off cascades of inflammatory responses. Trauma patients with evidence of subclinical GI ischemia have been shown to have poor outcomes. Gastric tonometry, by detecting the presence of gastric intramucosal acidosis as a proxy of splanchnic hypoperfusion, may facilitate more timely and rational shock resuscitation. This article reviews the development and validation of gastric tonometry and summarizes the clinical studies that have used this modality to guide the management of shock in trauma patients.

Original languageEnglish (US)
Pages (from-to)475S-481S
JournalChest
Volume123
Issue number5 SUPPL.
StatePublished - May 1 2003

Keywords

  • Gastric tonometry
  • Mucosal acidosis
  • Shock

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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    Hameed, S. M., & Cohn, S. M. (2003). Gastric tonometry: The role of mucosal pH measurement in the management of trauma. Chest, 123(5 SUPPL.), 475S-481S.