Gas plasma treatment of poly(DL-lactic acid) films and its influence on the adhesion and proliferation of osteoblast-like cells

C. M. Alves, Y. Yang, D. L. Carnes, J. L. Ong, V. L. Sylvia, D. D. Dean, R. L. Reis, C. M. Agrawal

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The biological reponse to poly(lactic acid), modified by radio frequency glow discharge (RFGD), was determined using two bone cell types which include a cell line and a primary culture. The poly[DL-lactide] (PDLLA) films were fabricated by direct casting of polymer-acetone solution over 1.5 cm diameter glass coveslips under clean conditions. The surfaces of the films were modified by means of O2 gas plasma in a RFGD chamber. These films were sterilized by ultraviolet (UV) radiation and stored under vacuum. The characterization of the effects of plasma treatment was done by measuring the surface wettability, adhesion tension of water and surface energy.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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    Alves, C. M., Yang, Y., Carnes, D. L., Ong, J. L., Sylvia, V. L., Dean, D. D., Reis, R. L., & Agrawal, C. M. (2004). Gas plasma treatment of poly(DL-lactic acid) films and its influence on the adhesion and proliferation of osteoblast-like cells. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).