Gas-liquid chromatography of derivatives of several amino acids that occur in the actinomycins

Martha A. Ward, Timothy E. McCarthy, Jonathan S. Nishimura

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The gas-liquid chromatography of the n-amyl N-acetyl ester derivatives of a number of amino acids known to occur in the actinomycins is described. Preliminary studies indicate that this procedure may be employed in the analysis of hydrolyzates of these antibiotics with a sensitivity of at least 10-9 mole. Application of the procedure to the determination of the carboxyl terminal amino acids in an actinomycin is also described.

Original languageEnglish (US)
Pages (from-to)275-281
Number of pages7
JournalAnalytical Biochemistry
Volume20
Issue number2
DOIs
StatePublished - Aug 1967
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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