Garlic (Allium sativum): A review of its relationship to cancer

H. Sumiyoshi, M. J. Wargovich

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Garlic has long been considered a herb with curative power. From ancient times to the present, interest has been maintained in alliums by scientists seeking evidence of the reported efficacy of garlic towards cancer. Garlic and other alliums are rich sources of organosulfur compounds. Sulfur compounds in garlic and onion have pharmacological activity. Recent studies have shown that the principle thioethers in garlic have anticarcinogenic effects, that is, the ability to inhibit the carcinogenic process. Such studies have shown that chemicals in garlic inhibit both phases of carcinogenesis, namely, inhibition and promotion. Epidemiological studies only recently completed suggest a cancer preventive role for allium vegetables in humans. Thus organosulfur compounds in garlic may be effective agents for cancer chemoprevention trials in man.

Original languageEnglish (US)
Pages (from-to)133-140
Number of pages8
JournalAsia Pacific Journal of Pharmacology
Volume4
Issue number2
StatePublished - Jan 1 1989
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology

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