Abstract
Garlic has long been considered a herb with curative power. From ancient times to the present, interest has been maintained in alliums by scientists seeking evidence of the reported efficacy of garlic towards cancer. Garlic and other alliums are rich sources of organosulfur compounds. Sulfur compounds in garlic and onion have pharmacological activity. Recent studies have shown that the principle thioethers in garlic have anticarcinogenic effects, that is, the ability to inhibit the carcinogenic process. Such studies have shown that chemicals in garlic inhibit both phases of carcinogenesis, namely, inhibition and promotion. Epidemiological studies only recently completed suggest a cancer preventive role for allium vegetables in humans. Thus organosulfur compounds in garlic may be effective agents for cancer chemoprevention trials in man.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 133-140 |
| Number of pages | 8 |
| Journal | Asia Pacific Journal of Pharmacology |
| Volume | 4 |
| Issue number | 2 |
| State | Published - 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Pharmacology
Cite this
Garlic (Allium sativum) : A review of its relationship to cancer. / Sumiyoshi, H.; Wargovich, Michael J.
In: Asia Pacific Journal of Pharmacology, Vol. 4, No. 2, 1989, p. 133-140.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Garlic (Allium sativum)
T2 - A review of its relationship to cancer
AU - Sumiyoshi, H.
AU - Wargovich, Michael J
PY - 1989
Y1 - 1989
N2 - Garlic has long been considered a herb with curative power. From ancient times to the present, interest has been maintained in alliums by scientists seeking evidence of the reported efficacy of garlic towards cancer. Garlic and other alliums are rich sources of organosulfur compounds. Sulfur compounds in garlic and onion have pharmacological activity. Recent studies have shown that the principle thioethers in garlic have anticarcinogenic effects, that is, the ability to inhibit the carcinogenic process. Such studies have shown that chemicals in garlic inhibit both phases of carcinogenesis, namely, inhibition and promotion. Epidemiological studies only recently completed suggest a cancer preventive role for allium vegetables in humans. Thus organosulfur compounds in garlic may be effective agents for cancer chemoprevention trials in man.
AB - Garlic has long been considered a herb with curative power. From ancient times to the present, interest has been maintained in alliums by scientists seeking evidence of the reported efficacy of garlic towards cancer. Garlic and other alliums are rich sources of organosulfur compounds. Sulfur compounds in garlic and onion have pharmacological activity. Recent studies have shown that the principle thioethers in garlic have anticarcinogenic effects, that is, the ability to inhibit the carcinogenic process. Such studies have shown that chemicals in garlic inhibit both phases of carcinogenesis, namely, inhibition and promotion. Epidemiological studies only recently completed suggest a cancer preventive role for allium vegetables in humans. Thus organosulfur compounds in garlic may be effective agents for cancer chemoprevention trials in man.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024345879&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0024345879
VL - 4
SP - 133
EP - 140
JO - Asia Pacific Journal of Pharmacology
JF - Asia Pacific Journal of Pharmacology
SN - 0217-9687
IS - 2
ER -