Gallium-67/Technetium-99m methylene diphosphonate ratio imaging: Early rabbit osteomyelitis and fracture

M. F. Hartshorne; G. Graham; J. Lancaster; D. Berger

Gallium-67/Technetium-99m methylene diphosphonate ratio imaging: Early rabbit osteomyelitis and fracture

M. F. Hartshorne, G. Graham, J. Lancaster, D. Berger

Research output: Contribution to journal › Article › peer-review

Abstract

Simultaneous digital acquisition of [⁶⁷Ga] and [^99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphylococcus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential ⁶⁷Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.

Original language	English (US)
Pages (from-to)	272-277
Number of pages	6
Journal	Journal of Nuclear Medicine
Volume	26
Issue number	3
State	Published - Dec 1 1985
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Gallium-67/Technetium-99m methylene diphosphonate ratio imaging: Early rabbit osteomyelitis and fracture",

abstract = "Simultaneous digital acquisition of [67Ga] and [99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphylococcus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential 67Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.",

author = "Hartshorne, {M. F.} and G. Graham and J. Lancaster and D. Berger",

year = "1985",

month = dec,

day = "1",

language = "English (US)",

volume = "26",

pages = "272--277",

journal = "Journal of Nuclear Medicine",

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}

TY - JOUR

T1 - Gallium-67/Technetium-99m methylene diphosphonate ratio imaging

T2 - Early rabbit osteomyelitis and fracture

AU - Hartshorne, M. F.

AU - Graham, G.

AU - Lancaster, J.

AU - Berger, D.

PY - 1985/12/1

Y1 - 1985/12/1

N2 - Simultaneous digital acquisition of [67Ga] and [99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphylococcus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential 67Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.

AB - Simultaneous digital acquisition of [67Ga] and [99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphylococcus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential 67Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.

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SN - 0161-5505

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