Gallium-67/Technetium-99m methylene diphosphonate ratio imaging: Early rabbit osteomyelitis and fracture

M. F. Hartshorne, G. Graham, J. Lancaster, D. Berger

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Simultaneous digital acquisition of [67Ga] and [99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphylococcus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential 67Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.

Original languageEnglish (US)
Pages (from-to)272-277
Number of pages6
JournalJournal of Nuclear Medicine
Volume26
Issue number3
StatePublished - Dec 1 1985
Externally publishedYes

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ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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