Further Studies of Gastric Hypersecretion in Chronic Renal Failure

A. M.M. Shepherd, W. K. Stewart, B. Thjodleifsson, K. G. Wormsley

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

The effect of medical treatment has been studied in four patients with end-stage renal failure who suffered from severe spontaneous gastric hypersecretion, associated with very low levels of intraduodenal pH in two cases. Atropine decreased the overnight gastric acid output, but the residual acid secretion and duodenal content of acid remained dangerously high in one of the patients. Secretin inhibited the basal gastric secretion of acid in all cases and converted the pH of the duodenal contents to alkaline. While atropine cannot be used to control the gastric hypersecretion, secretin may prove to be valuable in the therapeutic management of the gastric hypersecretion of patients with chronic renal failure.

Original languageEnglish (US)
Pages (from-to)96-98
Number of pages3
JournalBritish Medical Journal
Volume1
Issue number5898
DOIs
StatePublished - Jan 19 1974

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Further Studies of Gastric Hypersecretion in Chronic Renal Failure'. Together they form a unique fingerprint.

Cite this