Fungal peritonitis in patients on continuous ambulatory peritoneal dialysis.

C. M. Kerr, J. R. Perfect, P. C. Craven, J. H. Jorgensen, D. J. Drutz, J. D. Shelburne, H. A. Gallis, R. A. Gutman

Research output: Contribution to journalReview article

164 Scopus citations

Abstract

Fungal peritonitis is a rare complication in patients on continuous ambulatory peritoneal dialysis. We report five recent cases and their management. The fungi isolated were Candida albicans, C. parapsilosis, Exophiala jeanselmei, Drechslera spicifera, and a Fusarium species. Chemotherapy was attempted with various regimens including oral ketoconazole, intravenous or intraperitoneal amphotericin B, and oral flucytosine. Pharmacokinetic studies were done in two patients receiving treatment with one of these drugs. Three patients were cured of their fungal infection. Three patients whose Tenckhoff catheters were left in situ died, whereas two patients whose catheters were removed survived. Our experience suggests that removal of the peritoneal catheter should be considered once the diagnosis of fungal peritonitis is established.

Original languageEnglish (US)
Pages (from-to)334-336
Number of pages3
JournalAnnals of internal medicine
Volume99
Issue number3
DOIs
StatePublished - Sep 1983

ASJC Scopus subject areas

  • Internal Medicine

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