Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery

Sinasi Taner Yildiran, Fatih Mehmet Mutlu, Mehmet Ali Saracli, Yusuf Uysal, Ahmet Gonlum, Gungor Sobaci, Deanna A. Sutton

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The first case of postoperative endophthalmitis after cataract surgery caused by Aspergillus ustus, a species that has only rarely been implicated in human disease, is described. Six weeks after cataract surgery, a 67-year-old medically controlled diabetic patient presented with uveitis, mild ciliary injection and ocular discomfort. Anterior chamber paracentesis, vitreous tap and finally complete vitrectomy with removal of the capsular bag including the intraocular lens were performed and several sets of culture yielded A. ustus. Despite vigorous systemic (itraconazole and caspofungin) and intravitreal (amphotericin B and caspofungin) antifungal therapy, the endophthalmitis did not improve. The painful eye with marked inflammation was finally enucleated. In vitro susceptibility testing of the isolate showed that it appeared resistant to amphotericin B, caspofungin, itraconazole, voriconazole, and posaconazole, and susceptible to terbinafine.

Original languageEnglish (US)
Pages (from-to)665-669
Number of pages5
JournalMedical Mycology
Volume44
Issue number7
DOIs
StatePublished - Nov 2006

Fingerprint

caspofungin
Endophthalmitis
cataract
Aspergillus
Cataract
Itraconazole
itraconazole
terbinafine
surgery
amphotericin B
Amphotericin B
eyes
Paracentesis
Intraocular Lenses
Vitrectomy
Uveitis
Anterior Chamber
Lens
human diseases
bags

Keywords

  • Aspergillus ustus
  • Cataract surgery
  • Endophthalmitis

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • veterinary(all)
  • Microbiology

Cite this

Taner Yildiran, S., Mehmet Mutlu, F., Ali Saracli, M., Uysal, Y., Gonlum, A., Sobaci, G., & Sutton, D. A. (2006). Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery. Medical Mycology, 44(7), 665-669. https://doi.org/10.1080/13693780600717161

Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery. / Taner Yildiran, Sinasi; Mehmet Mutlu, Fatih; Ali Saracli, Mehmet; Uysal, Yusuf; Gonlum, Ahmet; Sobaci, Gungor; Sutton, Deanna A.

In: Medical Mycology, Vol. 44, No. 7, 11.2006, p. 665-669.

Research output: Contribution to journalArticle

Taner Yildiran, S, Mehmet Mutlu, F, Ali Saracli, M, Uysal, Y, Gonlum, A, Sobaci, G & Sutton, DA 2006, 'Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery', Medical Mycology, vol. 44, no. 7, pp. 665-669. https://doi.org/10.1080/13693780600717161
Taner Yildiran S, Mehmet Mutlu F, Ali Saracli M, Uysal Y, Gonlum A, Sobaci G et al. Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery. Medical Mycology. 2006 Nov;44(7):665-669. https://doi.org/10.1080/13693780600717161
Taner Yildiran, Sinasi ; Mehmet Mutlu, Fatih ; Ali Saracli, Mehmet ; Uysal, Yusuf ; Gonlum, Ahmet ; Sobaci, Gungor ; Sutton, Deanna A. / Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery. In: Medical Mycology. 2006 ; Vol. 44, No. 7. pp. 665-669.
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