Fungal disease of the nose and paranasal sinuses

George R. Thompson, Thomas F. Patterson

Research output: Contribution to journalArticlepeer-review

96 Scopus citations


Fungal infections of the nose and paranasal sinuses represent a spectrum of diseases ranging from colonization to invasive rhinosinusitis. Clinical manifestations are largely dependent on the immune status of the host, and given the ubiquitous nature of these organisms, exposure is unavoidable. Noninvasive disease includes asymptomatic fungal colonization, fungus balls, and allergic fungal rhinosinusitis. Invasive disease includes indolent chronic rhinosinusitis, granulomatous fungal sinusitis, and acute fulminant fungal rhinosinusitis. A differentiation of these somewhat overlapping syndromes and the disparate treatment regimens required for effective management are the focus of this review.

Original languageEnglish (US)
Pages (from-to)321-326
Number of pages6
JournalJournal of Allergy and Clinical Immunology
Issue number2
StatePublished - Feb 2012
Externally publishedYes


  • Fungal colonization
  • acute fulminant fungal rhinosinusitis
  • allergic fungal rhinosinusitis
  • chronic rhinosinusitis
  • fungus balls
  • granulomatous fungal sinusitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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