Fundus autofluorescence in the diagnosis and monitoring of acute retinal necrosis

Tyson S.J. Ward, Ashvini K. Reddy

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Background: Acute retinal necrosis (ARN), a vision threatening viral retinitis, is often diagnosed and treated based on clinical findings. These clinical features have been well characterized by various imaging modalities, but not using fundus autofluorescence (FAF), a noninvasive method of evaluating the neurosensory retina and retinal pigment epithelium (RPE) based on the detection of endogenous fluorophores. Findings: A patient diagnosed with ARN was followed over a 10-month period to identify and document the fundus findings using FAF imaging. Pathological changes present at the level of the neurosensory retina and RPE in ARN can be detected and characterized using fundus autofluorescence imaging. Conclusions: The borders of disease activity in ARN correlate with high-contrast changes in autofluorescence patterns to facilitate monitoring of disease progression.

Original languageEnglish (US)
Article number19
JournalJournal of Ophthalmic Inflammation and Infection
Volume5
Issue number1
DOIs
StatePublished - Dec 24 2015
Externally publishedYes

Keywords

  • Acute retinal necrosis
  • Fundus autofluorescence

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases

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