Functional coactivation map of the human brain

Roberto Toro, Peter T. Fox, Tomáš Paus

Research output: Contribution to journalArticlepeer-review

272 Scopus citations

Abstract

Understanding the interactions among different brain regions is fundamental to our understanding of brain function. Here we describe a complete map of functional connections in the human brain derived by an automatic meta-analysis of 825 neuroimaging articles, representing 3402 experiments. The likelihood of a functional connection between regions was estimated by studying the interdependence of their "activity," as reported in each experiment, across all experiments. We obtained a dense coactivation map that recovers some fundamental principles of the brain's functional connectivity, such as the symmetric interhemispheric connections, and important functional networks, such as the fronto-parietal attention network, the resting state network and the motor network.

Original languageEnglish (US)
Pages (from-to)2553-2559
Number of pages7
JournalCerebral Cortex
Volume18
Issue number11
DOIs
StatePublished - Nov 2008

Keywords

  • Brain mapping
  • Database
  • Functional connectivity
  • Human brain
  • Meta-analysis

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

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