Function of melatonin in thermoregulatory processes

Seppo Saarela, Russel J Reiter

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Accumulated information shows that, besides its role in the timing of seasonal reproduction, melatonin also plays an important role in seasonal thermoregulatory adjustments of animals including torpor and hibernation. Furthermore, melatonin has a crucial role in circadian thermoregulatory adjustments of body temperature (Tb). Melatonin appears to send signals to the preoptic area of anterior hypothalamus PoAH) where it adjusts the set point of Tb consistent with the metabolic rate of the animal. This new function for melatonin as a transducer mediating information about energy balance has been suggested in this review. Melatonin also adjusts the activity of the biological clock in vertebrates.

Original languageEnglish (US)
Pages (from-to)295-311
Number of pages17
JournalLife Sciences
Volume54
Issue number5
DOIs
StatePublished - 1994

Fingerprint

Melatonin
Animals
Torpor
Biological Clocks
Anterior Hypothalamus
Hibernation
Preoptic Area
Energy balance
Body Temperature
Transducers
Reproduction
Vertebrates
Clocks
Temperature

ASJC Scopus subject areas

  • Pharmacology

Cite this

Function of melatonin in thermoregulatory processes. / Saarela, Seppo; Reiter, Russel J.

In: Life Sciences, Vol. 54, No. 5, 1994, p. 295-311.

Research output: Contribution to journalArticle

Saarela, Seppo ; Reiter, Russel J. / Function of melatonin in thermoregulatory processes. In: Life Sciences. 1994 ; Vol. 54, No. 5. pp. 295-311.
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