From bench-to-bedside: Licensing and development of a mineral-organic bone adhesive for bone repair

Michael Brown, George W. Kay, David Cochran, Joseph Fiorellini, Brian Hess

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Statement of Purpose: Often times, after a traumatic event or progression of a chronic disease, surgeons and dentists use metal hardware such as plates, screws, artificial joints and other metallic implants to reconstruct the damage that was done to the skeletal system. In many cases, the bone tissue does not provide adequate support for the hardware necessary to complete the surgical repair. Recently a new material called Tetranite® (LaunchPad Medical, LLC, Lowell, MA) has been developed that would allow physicians to glue both bone and metal. Tetranite is a novel mineral-organic bone cement comprised of a blend of tetracalcium phosphate and phosphoserine (TTCP-PS) powder which react in an aqueous medium to form a self-setting material which adheres to both metal and bone in a wet field. Once set, Tetranite acts as a biocompatible, load bearing scaffold that is bioresorbed while gradually being replaced upon new bone formation. LaunchPad Medical currently holds the exclusive world-wide license from Stryker (Kalamazoo, MI) to develop this novel material in dental and orthopedic applications.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

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  • Cite this

    Brown, M., Kay, G. W., Cochran, D., Fiorellini, J., & Hess, B. (2019). From bench-to-bedside: Licensing and development of a mineral-organic bone adhesive for bone repair. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.