Frequent occurrence of rapid as well as delayed gastric emptying of a corn flakes and milk meal in clinical patients with gastrointestinal symptoms

Ida Mary Santiago-Maldonado, William T Phillips

Research output: Contribution to journalArticle

Abstract

PURPOSE: Early satiety, nausea and vomiting have traditionally been associated with delayed gastric emptying (GE). A study was performed to determine the frequency of rapid/delayed GE in 100 patients sequentially referred for scintigraphic GE using a corn flakes and milk meal. METHODS AND MATERIALS: A retrospective review of 100 consecutive GE studies at the University Hospital, San Antonio, Texas, was performed. Each patient received a semisolid meal containing corn flakes, milk, and sugar (200 kcal, 6 g fat, 7 g protein, and 30 g carbohydrates) and 37.0 MBq (1 mCi) of Tc-99m sulfur colloid according to a standard clinical protocol followed by dynamic 1-minute planar acquisitions for 60 minutes. Gastric emptying times were classified based on the 50% emptying time as follows: 30 to 60 minutes for normal, abnormally delayed as >60 minutes, and abnormally rapid as <30 minutes. RESULTS: Twenty-eight patients demonstrated rapid GE, 25 delayed GE, and 45 normal GE. Fifteen (54%) patients with rapid GE were diabetic, 4 (14%) had impaired fasting glucose values, and 9 (32%) were normoglycemic. Fourteen (56%) patients with delayed GE were diabetic, one (4%) had impaired fasting glucose, and 10 (40%) were normoglycemic. Both patients with delayed and those with rapid GE had nausea as the most common symptom followed by early satiety (rapid GE) and vomiting (delayed GE). Of 28 patients with rapid GE, 26 were on promotility agents. CONCLUSION: The number of patients with rapid GE of the corn flakes, milk, and sugar meal is appreciably greater (28%) than previously reported with other meals. This relative large number is likely related to the meal composition and the homogeneous dispersal of the label within the meal.

Original languageEnglish (US)
Pages (from-to)186-193
Number of pages8
JournalClinical Nuclear Medicine
Volume32
Issue number3
DOIs
StatePublished - Mar 2007

Fingerprint

Gastric Emptying
Zea mays
Meals
Milk
Nausea
Vomiting
Fasting
Technetium Tc 99m Sulfur Colloid
Glucose
Clinical Protocols

Keywords

  • Delayed
  • Diabetes mellitus
  • Gastric emptying
  • Impaired fasting glucose
  • Nuclear
  • Rapid
  • Scintigraphic
  • Syndrome X

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Frequent occurrence of rapid as well as delayed gastric emptying of a corn flakes and milk meal in clinical patients with gastrointestinal symptoms. / Santiago-Maldonado, Ida Mary; Phillips, William T.

In: Clinical Nuclear Medicine, Vol. 32, No. 3, 03.2007, p. 186-193.

Research output: Contribution to journalArticle

@article{c50fc22966d44c4ca9f5eaf34cd41b8a,
title = "Frequent occurrence of rapid as well as delayed gastric emptying of a corn flakes and milk meal in clinical patients with gastrointestinal symptoms",
abstract = "PURPOSE: Early satiety, nausea and vomiting have traditionally been associated with delayed gastric emptying (GE). A study was performed to determine the frequency of rapid/delayed GE in 100 patients sequentially referred for scintigraphic GE using a corn flakes and milk meal. METHODS AND MATERIALS: A retrospective review of 100 consecutive GE studies at the University Hospital, San Antonio, Texas, was performed. Each patient received a semisolid meal containing corn flakes, milk, and sugar (200 kcal, 6 g fat, 7 g protein, and 30 g carbohydrates) and 37.0 MBq (1 mCi) of Tc-99m sulfur colloid according to a standard clinical protocol followed by dynamic 1-minute planar acquisitions for 60 minutes. Gastric emptying times were classified based on the 50{\%} emptying time as follows: 30 to 60 minutes for normal, abnormally delayed as >60 minutes, and abnormally rapid as <30 minutes. RESULTS: Twenty-eight patients demonstrated rapid GE, 25 delayed GE, and 45 normal GE. Fifteen (54{\%}) patients with rapid GE were diabetic, 4 (14{\%}) had impaired fasting glucose values, and 9 (32{\%}) were normoglycemic. Fourteen (56{\%}) patients with delayed GE were diabetic, one (4{\%}) had impaired fasting glucose, and 10 (40{\%}) were normoglycemic. Both patients with delayed and those with rapid GE had nausea as the most common symptom followed by early satiety (rapid GE) and vomiting (delayed GE). Of 28 patients with rapid GE, 26 were on promotility agents. CONCLUSION: The number of patients with rapid GE of the corn flakes, milk, and sugar meal is appreciably greater (28{\%}) than previously reported with other meals. This relative large number is likely related to the meal composition and the homogeneous dispersal of the label within the meal.",
keywords = "Delayed, Diabetes mellitus, Gastric emptying, Impaired fasting glucose, Nuclear, Rapid, Scintigraphic, Syndrome X",
author = "Santiago-Maldonado, {Ida Mary} and Phillips, {William T}",
year = "2007",
month = "3",
doi = "10.1097/01.rlu.0000255028.99539.d3",
language = "English (US)",
volume = "32",
pages = "186--193",
journal = "Clinical Nuclear Medicine",
issn = "0363-9762",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Frequent occurrence of rapid as well as delayed gastric emptying of a corn flakes and milk meal in clinical patients with gastrointestinal symptoms

AU - Santiago-Maldonado, Ida Mary

AU - Phillips, William T

PY - 2007/3

Y1 - 2007/3

N2 - PURPOSE: Early satiety, nausea and vomiting have traditionally been associated with delayed gastric emptying (GE). A study was performed to determine the frequency of rapid/delayed GE in 100 patients sequentially referred for scintigraphic GE using a corn flakes and milk meal. METHODS AND MATERIALS: A retrospective review of 100 consecutive GE studies at the University Hospital, San Antonio, Texas, was performed. Each patient received a semisolid meal containing corn flakes, milk, and sugar (200 kcal, 6 g fat, 7 g protein, and 30 g carbohydrates) and 37.0 MBq (1 mCi) of Tc-99m sulfur colloid according to a standard clinical protocol followed by dynamic 1-minute planar acquisitions for 60 minutes. Gastric emptying times were classified based on the 50% emptying time as follows: 30 to 60 minutes for normal, abnormally delayed as >60 minutes, and abnormally rapid as <30 minutes. RESULTS: Twenty-eight patients demonstrated rapid GE, 25 delayed GE, and 45 normal GE. Fifteen (54%) patients with rapid GE were diabetic, 4 (14%) had impaired fasting glucose values, and 9 (32%) were normoglycemic. Fourteen (56%) patients with delayed GE were diabetic, one (4%) had impaired fasting glucose, and 10 (40%) were normoglycemic. Both patients with delayed and those with rapid GE had nausea as the most common symptom followed by early satiety (rapid GE) and vomiting (delayed GE). Of 28 patients with rapid GE, 26 were on promotility agents. CONCLUSION: The number of patients with rapid GE of the corn flakes, milk, and sugar meal is appreciably greater (28%) than previously reported with other meals. This relative large number is likely related to the meal composition and the homogeneous dispersal of the label within the meal.

AB - PURPOSE: Early satiety, nausea and vomiting have traditionally been associated with delayed gastric emptying (GE). A study was performed to determine the frequency of rapid/delayed GE in 100 patients sequentially referred for scintigraphic GE using a corn flakes and milk meal. METHODS AND MATERIALS: A retrospective review of 100 consecutive GE studies at the University Hospital, San Antonio, Texas, was performed. Each patient received a semisolid meal containing corn flakes, milk, and sugar (200 kcal, 6 g fat, 7 g protein, and 30 g carbohydrates) and 37.0 MBq (1 mCi) of Tc-99m sulfur colloid according to a standard clinical protocol followed by dynamic 1-minute planar acquisitions for 60 minutes. Gastric emptying times were classified based on the 50% emptying time as follows: 30 to 60 minutes for normal, abnormally delayed as >60 minutes, and abnormally rapid as <30 minutes. RESULTS: Twenty-eight patients demonstrated rapid GE, 25 delayed GE, and 45 normal GE. Fifteen (54%) patients with rapid GE were diabetic, 4 (14%) had impaired fasting glucose values, and 9 (32%) were normoglycemic. Fourteen (56%) patients with delayed GE were diabetic, one (4%) had impaired fasting glucose, and 10 (40%) were normoglycemic. Both patients with delayed and those with rapid GE had nausea as the most common symptom followed by early satiety (rapid GE) and vomiting (delayed GE). Of 28 patients with rapid GE, 26 were on promotility agents. CONCLUSION: The number of patients with rapid GE of the corn flakes, milk, and sugar meal is appreciably greater (28%) than previously reported with other meals. This relative large number is likely related to the meal composition and the homogeneous dispersal of the label within the meal.

KW - Delayed

KW - Diabetes mellitus

KW - Gastric emptying

KW - Impaired fasting glucose

KW - Nuclear

KW - Rapid

KW - Scintigraphic

KW - Syndrome X

UR - http://www.scopus.com/inward/record.url?scp=33847179420&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33847179420&partnerID=8YFLogxK

U2 - 10.1097/01.rlu.0000255028.99539.d3

DO - 10.1097/01.rlu.0000255028.99539.d3

M3 - Article

C2 - 17314592

AN - SCOPUS:33847179420

VL - 32

SP - 186

EP - 193

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

IS - 3

ER -