Foreign body reaction to calcium hydroxylapatite after lip augmentation

Vidya Sankar, H. Stan McGuff

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Background. Dentists need to be aware of soft-tissue lesions resulting from cosmetic facial/lip procedures that involve the use of injectable materials. Common side effects detected on clinical examination may include edema, bruising and noninflammatory lip nodules. Case Description. A 51-year-old woman visited a dental clinic with the chief complaint of a lump on the mucosal aspect of her lower lip. She reported having noted the lesion a few weeks before seeking care at the clinic. Several weeks later, the lesion persisted and new lesions were detected. The clinician excised the initial lesion only. Clinical Implications. The lip nodules were associated with a cosmetic procedure and were inflammatory in nature. This is the first granulomatous response reported as a result of injections with calcium hydroxylapatite (Radiesse, BioForm Medical, San Mateo, Calif.). Poor patient recollection of his or her medical history may result in confusion with pathological processes such as infection, neoplasia or malignancy.

Original languageEnglish (US)
Pages (from-to)1093-1096
Number of pages4
JournalJournal of the American Dental Association
Issue number8
StatePublished - Aug 2007


  • Calcium hydroxylapatite
  • Cosmetic procedure
  • Dermal fillers
  • Side effects

ASJC Scopus subject areas

  • Dentistry(all)


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