Fluorescence imaging of early lung cancer

S. Lam; J. Hung; C. MacAulay; B. Jaggi; B. Palcic

Fluorescence imaging of early lung cancer

S. Lam, J. Hung, C. MacAulay, B. Jaggi, B. Palcic

Pediatrics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Using a ratio fluorometer probe, tissue autofluorescence induced by a krypton ion laser in normal bronchial tissues and early lung cancer was found to be different. In vivo spectroscopic measurements using an optical multichannel analyzer also showed an overall decrease in autofluorescence in the tumor tissues. Because tissue autofluorescence is not uniform, the technique of ratioing may not be reliably applied to bronchoscopic imaging of early lung cancer to cancel the dependence of fluorescence intensity on the distance, angle, and irradiance of the excitation light. This can, however, be overcome by other mathematical transformations of the autofluorescence images of the two spectral regions.

Original language	English (US)
Title of host publication	Biomedical Engineering Perspectives
Subtitle of host publication	Health Care Technologies for the 1990's and Beyond
Publisher	Publ by IEEE
Pages	1142-1143
Number of pages	2
Edition	pt 3
ISBN (Print)	0879425598
State	Published - Dec 1 1990
Event	Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA Duration: Nov 1 1990 → Nov 4 1990

Publication series

Name	Proceedings of the Annual Conference on Engineering in Medicine and Biology
Number	pt 3
ISSN (Print)	0589-1019

Other

Other	Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
City	Philadelphia, PA, USA
Period	11/1/90 → 11/4/90

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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Fluorescence imaging of early lung cancer. / Lam, S.; Hung, J.; MacAulay, C.; Jaggi, B.; Palcic, B.

Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond. pt 3. ed. Publ by IEEE, 1990. p. 1142-1143 (Proceedings of the Annual Conference on Engineering in Medicine and Biology; No. pt 3).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lam, S, Hung, J, MacAulay, C, Jaggi, B & Palcic, B 1990, Fluorescence imaging of early lung cancer. in Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond. pt 3 edn, Proceedings of the Annual Conference on Engineering in Medicine and Biology, no. pt 3, Publ by IEEE, pp. 1142-1143, Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Philadelphia, PA, USA, 11/1/90.

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